Formulasi Granul Effervescent Ekstrak Daun Leilem (Clerodendrum minahassae L)

Authors

  • Fabiola N Palobo
  • Paulina V. Y. Yamlean
  • Adithya Yudistira

DOI:

https://doi.org/10.35799/pha.1.2012.488

Abstract

Leilem Leaves had a bitter taste, but it is believed as antioxidant. This research aims to find way for
making a formulation of effervescent granules from Leilem leaves extract wich is demand the
standards for effervescent granules. The extracts resulted from soxhletasi method with 95% ethanol
(1:5), and the formula based from 7% extract, citric acid 16.2%, 25.2% tartaric acid, lemon essence
2%, 0.5% CMC, and food coloring. Effervescent granules from Leilem leaves are prepared by dry
granulation method. Results of manufacturing effervescent granules was tested by physical stuff, and
then compared with the literature, the test results showed effervescent granules have a regularly
shape, with orange-scented, had a 4.35% value of LOD, the pour volume is 150g/183mL with 1.09%
volume of shrinkage, the test flow capacity is 30.650, and able to complete the test of dispersion time
for 1 minute 9 seconds. Based on these results it can be concluded that the extract of Leilem leaves
can be made an effervescent granules by dry granulation method, and has a good quality because it
was demand the standards test of good granules.
Key word: Clerodendrum minahassae L, Ekstract, Formulation, Effervescent

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Published

2012-11-01

How to Cite

Palobo, F. N., Yamlean, P. V. Y., & Yudistira, A. (2012). Formulasi Granul Effervescent Ekstrak Daun Leilem (Clerodendrum minahassae L). PHARMACON, 1(2). https://doi.org/10.35799/pha.1.2012.488

Issue

Vol. 1 No. 2 (2012)

Section

Articles

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