AKTIVITAS SITOTOKSIK EKSTRAK KARANG LUNAK Xenia sp. DARI TELUK MANADO, PROVINSI SULAWESI UTARA

Authors

  • Juniarti S Datula’bi FPIK UNSRAT
  • Robert A Bara FPIK UNSRAT
  • Fitje Losung FPIK UNSRAT
  • Remy EP Mangindaan FPIK UNSRAT
  • Ping A Angmalisang FPIK UNSRAT
  • Rose OSE Mantiri FPIK UNSRAT

DOI:

https://doi.org/10.35800/jplt.9.3.2021.36523

Abstract

Bioactive compounds from the sea which are generally in the form of secondary metabolites have the potential to be developed as medicinal ingredients. Marine life can be used as an object of research and development, considering the many benefits that can be taken from the secondary metabolite compounds contained in it, especially compounds that have bioactivity. Soft corals are marine biota that have bioactivity, extracts from sost coral contain bioactive compounds that have cytotoxic, anti-tumor, anti-viral, anti-inflammatory, anti-fungal, anti-leukemic, and enzyme activity inhibitory properties. Some of the research results show that marine soft corals have a variety of structures and biological activities including antioxidant substances. Soft corals were extracted by maceration method and then evaporated. The cytotoxic activity of soft coral extract was tested using the BLSA method and then analyzed the data to find the concentration of mortality (LC50). The purpose of this study was to test the cytotoxic activity of soft coral Xenia sp. The results of this study were testing the cytotoxic activity of the sample Xenia sp., amounting to 20.89 ppm, and having strong toxic properties.

Key words: BLSA, Soft coral Xenia sp., LC50, Cytotoxic

Author Biographies

Juniarti S Datula’bi, FPIK UNSRAT

Mahasiswa PS Ilmu Kelautan

Robert A Bara, FPIK UNSRAT

Dosen Program Studi Ilmu Kelautan

Fitje Losung, FPIK UNSRAT

DOSEN PS IK

Remy EP Mangindaan, FPIK UNSRAT

dosen PS IK

Ping A Angmalisang, FPIK UNSRAT

DOSEN PS IK

Rose OSE Mantiri, FPIK UNSRAT

DOSEN PS MSP

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How to Cite

Datula’bi, J. S., Bara, R. A., Losung, F., Mangindaan, R. E., Angmalisang, P. A., & Mantiri, R. O. (2021). AKTIVITAS SITOTOKSIK EKSTRAK KARANG LUNAK Xenia sp. DARI TELUK MANADO, PROVINSI SULAWESI UTARA. JURNAL PESISIR DAN LAUT TROPIS, 9(3), 66–73. https://doi.org/10.35800/jplt.9.3.2021.36523