PENGUJIAN EFEK DIURETIK SARI WORTEL (Daucus carota L.) PADA TIKUS PUTIH JANTAN GALUR WISTAR (Rattus norvegicus)

Mery A R Sinaga, Widdhi Bodhi, Paulina V Y Yamlean

Abstract


Carrot (Daucus carota L.) is a plant which used as traditional medicine and one of its benefits is
as diuretic. The research was aimed to find out diuretic effect of Carrot juice and relationship of
the increases of Carrot juice (Daucus carota L.) concentration on white male mice strain Wistar
(Rattus norvegicus). Fifteen mices were divided into five group of treatment, namely negative
control group (CMC 1% suspension), positive control group (furosemid suspension), 15%
suspension of carrot juice group, 30% suspension of carrot juice group and 60% suspension of
Carrot juice group.The test of diuretic effect were conducted by calculate volume of excreted
urine during 24 hours treatment. Data were analyzed using spss ver.19. The differences between
treatments were analyzed using one way ANOVA.The result shows that suspension of Carrot
juice treatment increase urine volume. The increases of juice concentration shows better effect.
Based on result, it can be concluded that Carrot juice possess diuretic effect (p<0,05), and there
are correlation between concentrations of Carrot juice to the increasing of urine
volume.Keywords : Carrot juice, diuretic effect, Rattus norvegicus

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DOI: https://doi.org/10.35799/pha.1.2012.484

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Publisher :
Pharmacy Study Program,
Faculty of Mathematic and Science
Sam Ratulangi University
Manado, North Sulawesi, Indonesia, 95115

     

Cooperation With :
Persatuan Ahli Farmasi Indonesia (PAFI)
Sulawesi Utara
Manado, North Sulawesi, Indonesia, 95112

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