FORMULASI DAN UJI STABILITAS FISIK SEDIAAN MASKER GEL PEEL-OFF EKSTRAK ETANOL DAUN MIANA (Coleus Scutelleroides (L.) Benth.) DENGAN BERBAGAI BASIS

Indriyani Arman,Hosea Jaya Edy, Karlah L.R Mansauda

Abstract


Abstract

Miana leaves (Coleus Scutelleroides (L.) Benth.) contained flavonoid compounds that has antioxidants properties. This study aimed to formulate peel-off gel mask ethanol extract from Miana leaves became peel-off gel mask that is physically stable and to knows the type of base that form a formulation with good physical quality based on the test parameters of physical properties and the stability of preparation. Formulation  of peel-off gel mask ethanol extract of miana leaves used three different types of base, they are HPMC, Carbopol, and Na.CMC. Each formula is differentiated based on base of concentration which were HPMC 4%, carbopol 1%, and Na.CMC 3%. Evaluation to predict the physical stability of the preparation included organoleptic test, homogeneity test, pH test, dispersion test, adhesion test and dry time test. In stability test, each formula is placed at temperature 27 oC for 28 days and made observation on the 1st, 7th, 14th, 21th, and 28th day. Based on the result, the ethanol extract of Miana leaves can be formulated into a peel-off mask and formulation with HPMC and Carbopol base has a good physical quality and physically stable compared to Na.CMC base.

Keywords: Miana Leaves, Peel-Off Gel Mask, Stability Teh

 

 

Abstrak

Daun Miana (Coleus Scutelleroides (L.) Benth.) memiliki kandungan senyawa flavonoid yang berkhasiat sebagai antioksidan. Penelitian ini bertujuan untuk memformulasikan ekstrak etanol daun Miana menjadi masker gel peel-off yang stabil secara fisik serta mengetahui jenis basis yang membentuk formulasi sediaan masker dengan mutu fisik yang baik berdasarkan parameter uji sifat fisik dan stabilitas sediaan. Formulasi sediaan masker gel peel-off  ekstrak etanol daun Miana dibuat dengan menggunakan tiga jenis basis yang berbeda yaitu HPMC, karbopol, dan Na.CMC. Masing-masing formula dibedakan berdasarkan basis konsentrasi yaitu HPMC 4%, karbopol 1%, dan Na.CMC 3%. Evaluasi yang dilakukan terhadap stabilitas fisik sediaan masker gel peel-off meliputi uji organoleptis, uji homogenitas, uji pH, uji daya sebar, uji daya lekat, dan uji waktu mengering. Uji stabilitas dilakukan pada suhu kamar (27 oC) selama 28 hari dan dilakukan pengamatan pada hari ke 1, 7, 14, 21, dan 28. Hasil uji stabilitas fisik sediaan masker gel peel-off ekstrak etanol daun Miana dapat diformulasikan dalam bentuk sediaan masker gel peel-off , dan formula masker dengan basis HPMC dan karbopol memiliki mutu fisik yang baik dan stabil secara fisik dibandingkan dengan basis Na.CMC.

Kata kunci: Daun Miana, Masker gel peel-off, Uji Stabilitas.


Keywords


Daun Miana; Masker gel peel-off; Uji Stabilitas

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DOI: https://doi.org/10.35799/pmj.4.1.2021.34523

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