@article{Toding Labi_Panda_Jim_2022, title={Right Ventricle Dysfunction in COVID-19 Patients}, volume={10}, url={https://ejournal.unsrat.ac.id/v3/index.php/eclinic/article/view/37751}, DOI={10.35790/ecl.v10i1.37751}, abstractNote={<p><strong>Abstract</strong>: Coronavirus disease 2019 (COVID-19) has become a global pandemic. Related to its pathomechanisms and complications, COVID-19 is identified as a complex multi-organ disease. Cardiac involvement is reported in COVID-19 patients. One of the cardiovascular complications of COVID-19 is right ventricular dysfunction. This study aimed to provide an overview of right ventricular dysfunction in COVID-19 patients and its association with the patient’s clinical outcomes. This was a literature review study conducted by searching and reviewing literatures on online databases as follows: PubMed, ScienceDirect, and ProQuest. There were 14 literatures obtained in this study with a total of 1,435 patients. All articles were observational studies conducted in January-April 2020 across various countries. Samples of patients with right ventricular dysfunction ranged from 3.6 to 41.7% of the total population of each study. Most studies defined right ventricle dysfunction as TAPSE<16-17 mm. Several echocardiography parameters and their threshold values were as follows: RV S’ <9,5-10 cm/s; RVFAC <35%; right ventricular free wall strain (RVFWS); and right ventricular global longitudinal strain (RVGLS) according to ASE guidelines. In conclusion, right ventricular dysfunction has a high prevalence and is associated with poor outcomes of COVID-19 patients. Transthoracic echocardiography examination might become a risk stratification modality in hospitalized COVID-19 patients.</p><p><strong>Keywords</strong>: right ventricular dysfunction; coronavirus disease 2019; transthoracic echocardiography</p><p><em> </em></p><p><strong>Abstrak: </strong><em>Coronavirus disease </em>2019 (COVID-19) telah menjadi pandemi global. Terkait dengan patomekanisme dan komplikasinya, COVID-19 dinyatakan sebagai penyakit multi-organ kompleks. Telah dilaporkan adanya keterlibatan jantung pada COVID-19. Salah satu komplikasi kardiovaskular dari COVID-19 ialah disfungsi ventrikel kanan. Penelitian ini bertujuan untuk memberikan gambaran disfungsi ventrikel kanan pada pasien COVID-19 dan hubungannya terhadap luaran klinis pasien. Jenis penelitian ialah <em>literature review</em>. Melalui penelusuran pada tiga <em>database</em> (<em>PubMed</em>, <em>ScienceDirect</em>, <em>ProQuest</em>), didapatkan 14 literatur dengan total 1.435 pasien. Semua artikel merupakan studi observasional yang dilakukan pada Januari-April 2020 dan tersebar di berbagai negara. Sampel pasien dengan disfungsi ventrikel kanan tercatat berkisar antara 3,6-41,7% dari total populasi tiap studi. Sebagian besar studi menetapkan definisi disfungsi ventrikel kanan dengan nilai TAPSE<16-17 mm. Beberapa parameter ekokardiografi lain beserta nilai ambang yang digunakan yaitu: RV S’ <9,5-10 cm/s; RVFAC <35%; serta <em>right ventricular free wall strain </em>(RVFWS) dan <em>right ventricular global longitudinal strain </em>(RVGLS) berdasarkan panduan ASE. Simpulan penelitian ini ialah disfungsi ventrikel kanan pada COVID-19 memiliki prevalensi tinggi dan berhubungan dengan luaran pasien yang buruk. Pemeriksaan ekokardiografi transtorakal dapat menjadi modalitas stratifikasi risiko pada pasien COVID-19 yang dirawat inap.</p><p><strong>Kata kunci</strong>: disfungsi ventrikel kanan; <em>coronavirus disease 2019</em>;<em> </em>ekokardiografi transtorakal</p>}, number={1}, journal={e-CliniC}, author={Toding Labi, Nikita P. and Panda, Agnes L. and Jim, Edmond L.}, year={2022}, month={Jan.}, pages={23–32} }