Atrophic Glossitis pada Defisiensi Nutrisi

Authors

  • Nurfadilah Nurfadilah Universitas Sam Ratulangi
  • Aurelia S. R. Supit Universitas Sam Ratulangi
  • Damajanty H. C. Pangemanan Universitas Sam Ratulangi

DOI:

https://doi.org/10.35790/eg.v11i2.46244

Abstract

In Indonesia, there are still many nutritional problems of poor nutrition, undernutrition or malnutrition. Oral manifestation usually found in nutritional deficiency is atrophic glossitis. This was a literature review study using Google Scholar, PubMed, and Science Direct databases. This study aimed to describe the incidence of atrophic glossitis in people with nutritional deficiencies.  After being selected based on inclusion and exclusion criteria, a critical appraisal was carried out and obtained eight literatures consisting of one cross-sectional, three case control, one prospective, and three retrospective studies. The results showed that the incidence of atrophic glossitis was found in 70.17% of people who had nutritional deficiency of vitamin B12; 34.4% in people with iron deficiency; 26.7% and 20.4% in people with nutritional deficiencies of iron, vitamin B12, and folic acid.  The micronutrient that was most often deficient in people with atrophic glossitis was vitamin B12. Besides that, there were also deficiencies of iron, folic acid, and zinc. Three articles showed the highest percentage of micronutrient deficits, namely vitamin B12; the other two articles described the highest percentage of iron deficiency. In conclusion, the incidence of atrophic glossitis is found in people with deficiencies in micronutrients of vitamin B12, iron, folic acid, and zinc.

Keywords: atrophic glossitis; nutritional deficiency; vitamin B12; iron; folic acid; zinc

 

Abstrak: Di Indonesia masih banyak ditemukan masalah gizi buruk dan gizi kurang atau malnutrisi. Manifestasi oral yang sering ditemukan pada penderita kurang gizi antara lain atrophic glossitis. Penelitian ini bertujuan untuk mengetahui gambaran kejadian atrophic glossitis pada individu yang mengalami defisiensi nutrisi. Jenis penelitian ialah suatu literature review dengan pencarian data menggunakan database Google Scholar, PubMed, dan Science Direct. Setelah diseleksi berdasarkan kriteria inklusi, dilakukan critical appraisal didapatkan delapan literatur terdiri dari satu studi cross-sectional, tiga case control, satu prospective dan tiga retrospective. Hasil penelitian menunjukkan bahwa kejadian atrophic glossitis ditemukan sebanyak 70,17% pada individu yang mengalami defisiensi nutrisi vitamin B12; 34,4% pada individu yang mengalami defisiensi nutrisi zat besi; 26,7% dan 20,4% pada individu yang mengalami defisiensi nutrisi zat besi, vitamin B12 dan asam folat. Jenis nutrisi mikro yang paling banyak mengalami defisit pada individu yang mengalami atrophic glossitis yaitu vitamin B12; selain itu terdapat juga defisiensi zat besi, asam folat dan zinc. Terdapat tiga artikel menunjukkan persentase defisit nutrisi mikro terbesar yaitu vitamin B12; dua artikel lainya menggambarkan persentase terbesar yaitu zat besi. Simpulan penelitian ini ialah kejadian atrophic glossitis didapatkan pada individu yang mengalami defisiensi nutrisi mikro vitamin B12, zat besi, asam folat dan zinc.

Kata kunci: atrophic glossitis; defisiensi nutrisi; vitamin B12; asam folat; zinc

Author Biographies

Nurfadilah Nurfadilah, Universitas Sam Ratulangi

Program Studi Pendidikan Dokter Gigi Fakultas Kedokteran Universitas Sam Ratulangi, Manado, Indonesia

Aurelia S. R. Supit, Universitas Sam Ratulangi

Program Studi Pendidikan Dokter Gigi Fakultas Kedokteran Universitas Sam Ratulangi, Manado, Indonesia

Damajanty H. C. Pangemanan, Universitas Sam Ratulangi

Program Studi Pendidikan Dokter Gigi Fakultas Kedokteran Universitas Sam Ratulangi, Manado, Indonesia

References

Menteri Kesehatan Republik Indonesia. Standar profesi gizi [Internet]. Jakarta: Departemen Kesehatan RI; 2007. p. 7. Available from: http://bppsdmk.kemkes.go.id/pusdiksdmk/wpcontent/uploads/ 2017/ 11/Penilaian-Status-Gizi-Final-SC.pdf.

Menteri Kesehatan Republik Indonesia. Penilaian status gizi [Internet]. Jakarta: Kementerian Kesehatan RI; 2017. 7 p. Available from: http://bppsdmk.kemkes.go.id/pusdiksdmk/wpcontent/uploads/ 2017/11/Penilaian-Status-GiziI-FinalL-SC.pdf.

Menteri Kesehatan Republik Indonesia. FAO: 768 juta penduduk dunia menderita kekurangan gizi pada 2020. Databooks [Internet]. 2020;2020. Available from: https://databoks.katadata.co.id/ datapublish/2021/11/11/fao-768-juta-penduduk-dunia-menderita-kekurangan-gizi-pada-2020.

Badan Penelitian dan Pengembangan kesehatan. Hasil riset kesehatan dasar tahun 2018. Vol. 53, Kementrian Kesehatan RI. Jakarta; 2018. p. 1689–99.

Thomas DM, Mirowski GW. Nutrition and oral mucosal diseases. Clin Dermatol [Internet]. 2010; 28(4):426–31. Available from: http://dx.doi.org/10.1016/j.clindermatol.2010.03.025.

Puspitasari AM, Ratnawati DE, Widodo AW. Klasifikasi penyakit gigi dan mulut menggunakan metode support vector machine. J-Ptiik [Internet]. 2018;2(2):1–9. Available from: http://j-ptiik.ub.ac.id.

Montes GR, Vilella KD, Bonotto DV, Martins MC, de Lima AAS. Atrophic glossitis as a clinical signs of severe anemia – Report of two cases. Polski Przegląd Otorynolaryngologiczny. 2014;3(4):201-4.

Demir N, Doǧan M, Koç A, Kaba S, Bulan K, Ozkol HU, et al. Dermatological findings of vitamin B12 deficiency and resolving time of these symptoms. Cutan Ocul Toxicol [Internet]. 2013;33(1):70–3. Available from: https://doi.org/10.3109/15569527.2013.861477.

Chiang CP, Chang JYF, Wang YP, Wu YC, Wu YH, Sun A. Significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in atrophic glossitis patients. J Formos Med Assoc [Internet]. 2018;117(12):1065–71. Available from: https://doi.org/10.1016/j.jfma.2018.07.016.

Alsheikh E, Amr E, Zahran F. Prevalence of oral manifestations of iron deficiency anemia in a sample of egyptian population. A hospital-based cross-sectional study. Adv Dent J. 2019;1(3):64–71.

Yu HW, Yu-Fong Chang J, Wang YP, Wu YC, Chen HM, Sun A. Hemoglobin, iron, vitamin B12, and folic acid deficiencies and hyperhomocysteinemia in behcet’s disease patients with atrophic glossitis. J Formos Med Assoc [Internet]. 2018;117(7):559–65. Available from: https: //doi.org/10.1016/j.jfma.2018.03.005.

Yang CW, Wang YP, Chang JYF, Cheng SJ, Chen HM, Sun A. Oral manifestations and blood profile in patients with iron deficiency anemia. J Formos Med Assoc [Internet]. 2013;113(2):83–7. Available from: http://dx.doi.org/10.1016/j.jfma.2013.11.010.

Sun A, Wang YP, Lin HP, Chen HM, Cheng SJ, Chiang CP. Significant reduction of homocysteine level with multiple B vitamins in atrophic glossitis patients. Oral Dis. 2013;19(5):519–24.

Radochová V, Slezák R, Radocha J. Oral manifestations of nutritional deficiencies: single centre analysis. Acta medica (Hradec Kral. 2020;63(3):95–100.

Bao ZX, Yang XW, Fang DD. Lingual linear lesions: A clinical sign strongly suggestive of severe vitamin B12 deficiency. Nutr Clin Pract. 2020;36(5):1041–8.

Lubis Z. Vitamin B12: Metabolisme dan fungsinya dalam tubuh. [Internet]. 2011;10. Available from: http://repository.usu.ac.id/handle/123456789/28179.

Chang JYF, Wang YP, Wu YC, Cheng SJ, Chen HM, Sun A. Hematinic deficiencies and pernicious anemia in oral mucosal disease patients with macrocytosis. J Formos Med Assoc [Internet]. 2015;114(8):736–41. Available from: http://dx.doi.org/10.1016/j.jfma.2015.03.015.

Gaurifa AMS. Hubungan asupan vitamin B9 dan vitamin B12 terhadap kadar hemoglobin anak balita gizi kurang usia 12-59 bulan di wilayah kerja puskesmas Petumbukan [Skripsi]. Medan: Politeknik Kesehatan Medan [Internet]; 2018. Available from: https://doi.org/10.1016/j.gecco.2018.

Melinda M, Putri M, Arman DA, Ramadhan W, Shofwan MA, Shafira A, et al. Patogenesis penyakit mukosa mulut akibat defisiensi nutrisi [Tugas OB5). Palembang: Universitas Sriwijaya; 2019.

Faot FF. Gambaran asupan zat gizi mikro dengan kejadian stunting pada balita usia 12-59 bulan di desa Lifuleo Kecamatan Kupang Barat Kabupaten Kupang. Available from: Repository Poltekkes Kupang (poltekeskupang.ac.id. 2019.

Bøhmer T, Mowé M. The association between atrophic glossitis and protein-calorie malnutrition in old age. Age Ageing. 2000;29(1):47–50.

Tzarina PA. Hubungan antara status nutrisi dengan keberadaan atrophic glossitis pada lansia (kajian pada penghuni panti jompo di Kabupaten Sleman, Kabupaten Bantul, dan Kotamadya Yogyakarta), J Online UGM. 2015. Available from: etd.repository.ugm.ac.id/home/detail_pencarian/79713

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Published

2023-05-06

How to Cite

Nurfadilah, N., Supit, A. S. R., & Pangemanan, D. H. C. (2023). Atrophic Glossitis pada Defisiensi Nutrisi. E-GiGi, 11(2), 252–257. https://doi.org/10.35790/eg.v11i2.46244

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