Efek Antifungi Sediaan Pasta Gigi Ekstrak Teh Hijau (Camellia sinensis L.) dan Peppermint (Menthapiperita) terhadap Candida albicans
DOI:
https://doi.org/10.35790/eg.v13i1.51629Abstract
Abstract: Candida albicans are normal flora of the oral cavity that are opportunistically pathogenic and becomes the main causative agent of oral candidiasis. The addition of herbal ingredients to toothpaste is a solution to resistance and synthetic antifungal side effects. Green tea and peppermint extracts are known to have an antifungal role with various active ingredients such as catechins, tannins, flavonoids, terpenoids, alkaloids, and saponins. This study aimed to determine the antifungal effect of toothpaste preparations of green tea extract and peppermint on C. albicans. This study used the agar diffusion method at several concentrations of green tea and peppermint extracts in toothpaste preparations, namely 1000 mg/ml, 500 mg/ml, 250 mg/ml, 125 mg/ml, 62,5 mg/ml and 31,25 mg/ml. The results showed that there was an antifungal effect of green tea and peppermint extract toothpaste against C. albicans at a concentration of 1000 mg/ml with an average inhibition zone diameter of 7.19 mm. The smallest inhibition zone was 125 mg/ml with a diameter of 1.16 mm. In conclusion, green tea and peppermint extract toothpastes have antifungal effects. The higher the concentration of the extract used in the toothpaste preparation, the greater the antifungal inhibition zone formed.
Keywords: Candida albicans; antifungal toothpaste; green tea; peppermint
Abstrak: Candida albicans merupakan flora normal rongga mulut yang bersifat patogen oportunistik dan menjadi agen penyebab utama kandidiasis oral. Penambahan bahan herbal pada pasta gigi mikroba merupakan solusi terhadap resistensi dan efek samping antijamur sintetik. Ekstrak teh hijau dan peppermint diketahui memiliki peran sebagai antijamur dengan berbagai kandungan aktifnya seperti katekin, tanin, flavonoid, terpenoid, alkaloid dan saponin. Mengetahui efek antifungi sediaan pasta gigi ekstrak teh hijau dan peppermint terhadap C. albicans. Penelitian ini menggunakan metode difusi agar dengan beberapa konsentrasi ekstrak teh hijau dan peppermint dalam sediaan pasta gigi yaitu 1000 mg/ml, 500 mg/ml, 250 mg/ml, 125 mg/ml, 62,5 mg/ml dan 31,25 mg/ml. Hasil penelitian memperlihatkan adanya efek antifungi pada pasta gigi ekstrak teh hijau dan peppermint terhadap C. albicans pada konsentrasi 1000 mg/ml dengan diameter zona hambat rata-rata sebesar 7,19 mm. Zona hambat terkecil dari konsentrasi 125 mg/ml dengan diameter 1,16 mm. Simpulan penelitian ini ialah pasta gigi ekstrak teh hijau dan peppermint memiliki efek antijamur. Semakin tinggi konsentrasi ekstrak yang digunakan dalam sediaan pasta gigi maka semakin besar zona hambat antijamur yang terbentuk.
Kata kunci: Candida albicans; pasta gigi antifungi; teh hijau; peppermint
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