Perbandingan Derajat Kristalinitas dan Konsentrasi Ion Kalsium Hidroksiapatit Tulang Sapi dengan Produk Komersial EthOss®
DOI:
https://doi.org/10.35790/eg.v13i2.61290Abstract
Abstract: Bone graft substitute materials are currently widely used in dentistry. Hydroxyapatite (HA) can be used as a bone graft material, but it is difficult to be absorbed properly. One of the materials that has been commercialized is EthOss® bone graft. This material has advantages that can be used in periodontal treatment. It has a unique calcium sulfate content that functions as a barrier to soft tissue, eliminating the need for additional collagen membranes. This study aimed to analyze and compare the degree of crystallinity and calcium content of EthOss® bone graft and hydroxyapatite. EthOss® and HA samples were prepared, then XRD and AAS tests were performed. The data obtained were then analyzed. The results showed that EthOss® bone graft had a crystallinity degree of 68.8%, and a calcium ion concentration of 24.2±0.3 mg/L. Meanwhile, hydroxyapatite had a crystallinity degree of91.7% and a calcium ion concentration of 8.8±1.0 mg/L. In conclusion, compared with hydroxyapatite, EthOss® bone graft has crystallinity that increases the degradation rate, mechanical strength, and osteoblast adhesion, as well as high solubility and release of calcium ions to support bone formation.
Keywords: EthOss®; hydroxyapatite; bone graft; crystallinity; calcium ions
Abstrak: Bone graft saat ini digunakan secara luas dalam bidang kedokteran gigi. Hidroksiapatit (HA) dapat digunakan sebagai material cangkok tulang, akan tetapi sulit terserap dengan baik. Salah satu material yang telah dikomersilkan ialah EthOss® bone graft. Material ini memiliki kelebihan bila digunakan dalam perawatan periodontal. Keunikannya yaitu kandungan kalsium sulfat yang berfungsi sebagai penghalang terhadap jaringan lunak sehingga menghilangkan kebutuhan akan membran kolagen tambahan. Penelitian ini bertujuan untuk menganalisis dan membandingkan derajat kristalinitas dan kandungan ion kalsium dalam EthOss® bone graft dan hidroksiapatit. Sampel EthOss® dan HA dipersiapkan, kemudian dilakukan uji XRD dan AAS. Data yang diperoleh kemudian dianalisis. Hasil penelitian mempelihatkan bahwa EthOss® bone graft memiliki derajat kritalinitas 68,8%, dan konsentrasi ion kalsium 24,2±0,3 mg/L sedangkan HA memiliki derajat kristalinitas 91,7% dan konsentrasi ion kalsium 8,8±1,0 mg/L. Simpulan penelitian ini dibandingkan dengan hidroksiapatit, EthOss® bone graft memiliki kristalinitas yang meningkatkan laju degradasi, kekuatan mekanik, dan adhesi osteoblas, serta kelarutan dan pelepasan ion kalsium tinggi untuk mendukung pembentukan tulang.
Kata kunci: EthOss®; hidroksiapatit; bone graft; kristalinitas; ion kalsium
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