Toxicity Test of Softcoral Lobophytum sp Against Artemia salina Shrimp, L Using the Brine Shrimp Lethality Method

Authors

  • Nickson J Kawung FPIK UNSRAT MANADO
  • Rizald M Rompas FPIK UNSRAT MANADO
  • Billy T Wagey FPIK UNSRAT MANADO
  • Adolfina Sumangando FMIPA UKIT TOMOHON
  • Hindang Kaempe UKIT TOmohon
  • Sonny Untu FMIPA UKIT TOMOHON
  • Royke R Palandi UKIT TOMOHON

DOI:

https://doi.org/10.35800/jplt.10.2.2022.41570

Abstract

Marine biota resources as a potential asset that can be used into various products including pharmaceutical products because they were a natural ingredient that very rich in biologically active compounds with a unique structure. Softcoral Lobophytum is one of the marine biota that has the secondary metabolites which can be useful in pharmacology field. The purpose of this study is to test the toxicity of the soft coral extract of Lobophytum sp as an anti-cancer biopotential. This research is using the Brine Shrime Lethality Test (BSLT) method, with laboratory experiments. Solfcoral samples were taken from Bunaken Island that using purposive sampling method. The test concentrations using 10, 100, 500 and 1000 ppm. The analysis toxicity using probit analysis for minitab program. The results showed that the increasing of concentration was followed by the increasing of the mortality number of the animal testing. The results of probit analysis obtained an LC50 value of 9.98 ppm. These results indicate that the bioactive substance of softcoral Lobophytum sp has the potential as an anti-cancer compound.

Keywords: Soft coral, Lobophytum sp, anti cancer, Artemia salina

Author Biographies

Nickson J Kawung, FPIK UNSRAT MANADO

Dosen Ilmu Kelautan FPIK Unsrat MAnado

Rizald M Rompas, FPIK UNSRAT MANADO

Diosen Program Studi Ilmu Kelautan FPIK UNSRAT

Billy T Wagey, FPIK UNSRAT MANADO

Dosen PSIlmu Kelautan FPIK UNSRAT

Adolfina Sumangando, FMIPA UKIT TOMOHON

Dosen PS Biologi FMIPA UKIT

Hindang Kaempe, UKIT TOmohon

Dosen FMIPA PS Biologi UKIT Tomohon

Sonny Untu, FMIPA UKIT TOMOHON

Dosen Progrma Studi Kimia FMIPA UKIT TOMOHON

Royke R Palandi, UKIT TOMOHON

Program Studi Farmasi FMIPA UKIT Tomohon

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How to Cite

Kawung, N. J., Rompas, R. M., Wagey, B. T., Sumangando, A., Kaempe, H., Untu, S., & Palandi, R. R. (2022). Toxicity Test of Softcoral Lobophytum sp Against Artemia salina Shrimp, L Using the Brine Shrimp Lethality Method. JURNAL PESISIR DAN LAUT TROPIS, 10(2), 33–38. https://doi.org/10.35800/jplt.10.2.2022.41570