FORMULASI DAN UJI KRIM EKSTRAK UMBI SINGKONG (Manihot esculenta) TERHADAP LUKA BAKAR PADA KELINCI (Oryctolagus cuniculus)

Authors

  • Inriani MarlinMareyke Rumayar
  • Paulina V. Y. Yamlean
  • Hosea Jaya Edy

DOI:

https://doi.org/10.35799/pha.1.2012.470

Abstract

Crops Cassava (Manihot esculenta) contains carbohydrates, phosphorus, calcium, vitamin
C, protein, iron and vitamin B1 can provide a healing effect on wounds. The content contained in
cassava able to give effect to the skin re-epithelialization of damaged tissues due to burns. This
study aims to determine the effectiveness of the test extract tubers Cassava (Manihot esculenta) in
the dosage form of a cream with the concentration level of 2%, 4%, and 8% for burn wound
healing in rabbits (Oryctolagus cuniculus). Making cream formulation using cassava tuber extract
oil phase in water and used as test animals 10 rabbits, divided into 5 treatment groups, namely, test
the cream treatment group, negative control group (basic cream) and a positive control group
(Bioplacenton). Burns in the back with a diameter of 1.5 cm were treated and observed the healing
effects for 7 days. The results showed that from day-1 to day-7 observations burns suffered
diminution in diameter. It was concluded that the concentration of 2% cassava extract cream has
healing effect and increasing the concentration of 4% and 8% contained showed more effective
and speed up the healing process.
Keywords: cream, extract, cassava tubers, healing burns, rabbit

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Published

2012-11-01

How to Cite

Rumayar, I. M., Yamlean, P. V. Y., & Edy, H. J. (2012). FORMULASI DAN UJI KRIM EKSTRAK UMBI SINGKONG (Manihot esculenta) TERHADAP LUKA BAKAR PADA KELINCI (Oryctolagus cuniculus). PHARMACON, 1(2). https://doi.org/10.35799/pha.1.2012.470

Issue

Vol. 1 No. 2 (2012)

Section

Articles

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