https://ejournal.unsrat.ac.id/v3/index.php/pharmacon <hr /> <table class="data" style="height: 252px;" width="798" bgcolor="#f0f0f0"> <tbody> <tr> <td align="justify"> <p>Journal title <strong> Pharmacon</strong></p> <p>Initials <strong> PHA</strong></p> <p>Abbreviation<strong> PHA</strong></p> <p>Frequency <strong>3 issues per year </strong></p> <p>ISSN <a href="https://issn.brin.go.id/terbit/detail/1579746176" target="_blank" rel="noopener"><strong>E-ISSN: 2721-4923</strong></a></p> <p>Editor in chief <strong>Yuanita Amalia Hariyanto</strong></p> <p>Publisher <strong>Universitas Sam Ratulangi</strong></p> </td> </tr> </tbody> </table> <p><strong>Pharmacon</strong> is the journal published by Pharmacy Study Program, Faculty of Mathematics and Natural Sciences, Sam Ratulangi University, Indonesia (<a title="P-ISSN: 2302-2493 E-ISSN: 2721-4923" href="https://issn.brin.go.id/terbit/detail/1579746176" target="_blank" rel="noopener"><strong>P-ISSN: 2302-2493</strong> <strong>E-ISSN: 2721-4923</strong></a>). Pharmacon was established in 2012 and published three times a year (February, June, and October).</p> <p>Pharmacon is an open access journal and has been indexed by main indexing <strong><a style="opacity: 1;" href="https://scholar.google.co.id/citations?hl=en&amp;view_op=list_works&amp;gmla=AJsN-F4yoOh69lFNWZeV-esTcAn8UlBqNZxXeFZXJn-gUphjDxn4bBh0dvPu-iMsg5_0yqDgdkXvZPBcy81MHLiMNvhvuaSHwg&amp;user=fDg43-EAAAAJ" target="_blank" rel="noopener">Google Scholar</a></strong>, <strong><a style="opacity: 1;" href="http://garuda.ristekbrin.go.id/journal/view/1015" target="_blank" rel="noopener">GARUDA</a></strong>, <strong><a href="https://search.crossref.org/" target="_blank" rel="noopener">Crossref</a></strong>.</p> <p>The editorial board welcomes original contributions of the author which never been published or under consideration for publication in any other publication. submission the journal should normally follow the <a title="PHA template" href="https://docs.google.com/document/d/1k_4fuD_X7JFboBKODObWs5Vj6EX0ir3f/edit?usp=sharing&amp;ouid=112625608935874045153&amp;rtpof=true&amp;sd=true" target="_blank" rel="noopener"><strong>PHA template.</strong></a></p> <hr /> UNIVERSITAS SAM RATULANGI en-US PHARMACON 2302-2493 <p>Authors who publish with this journal agree to the following terms:<br /><br /></p> <ol> <li>Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a <a href="https://creativecommons.org/licenses/by-nc/4.0/" rel="license">Creative Commons Attribution-NonCommercial 4.0 International License</a> that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.<br /><br /></li> <li>Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See <a href="http://opcit.eprints.org/oacitation-biblio.html" target="_new">The Effect of Open Access</a>)</li> </ol> https://ejournal.unsrat.ac.id/v3/index.php/pharmacon/article/view/52574 <p><em>Immunomodulators are drugs that can modify immune responses and stimulate natural defense mechanisms. Natural immunomodulator preparations are an alternative solution to using synthetic immunomodulators, because they are safer and have minimal side effects. The immunomodulatory in this research was made from underutilized pineapple skin. This research is focused on finding out the best formulation with varying concentrations of starch as a filler for immunomodulatory preparations from pineapple peel ethanol extract. Research methods include: pineapple peel preparation, extraction of secondary metabolite compounds from pineapple peel with ethanol solvent, phytochemical testing, capsule preparation formulation, and evaluation. Evaluation of capsule preparations: weight uniformity test, disintegration time test, flow velocity test, angle of repose test, and moisture content test. Phytochemical test results show that pineapple peel ethanol extract contains terpenoids, phenolics, flavonoids, alkaloids, steroids and tannins which have potential as immunomodulators. Formulation 1 has test results for angle of response, flow time, stable humidity, uniform weight, and does not break easily. Therefore, formulation 1 (starch 59.58 mg) is the best natural immunomodulator preparation from pineapple peel.</em></p> Vina Purnamasari M Copyright (c) 2024 Vina Purnamasari M https://creativecommons.org/licenses/by-nc/4.0 2024-10-31 2024-10-31 13 3 619 627 10.35799/pha.13.2024.52574