UJI AKTIVITAS ANTIBAKTERI EKSTRAK N-HEKSAN BIJI BUAH LANGSAT (Lansium domesticum Corr) TERHADAP BAKTERI Staphylococus Aureus DAN Klebsiella Pneumoniae

Authors

  • Anastasia P.R. Nurhamidin
  • Fatimawali Fatimawali
  • Irma Antasionasti

DOI:

https://doi.org/10.35799/pha.10.2021.32772

Abstract

ABSTRACT

 

Langsat fruit seeds (Lansium domesticum Corr) are  part of the plant that is known to be antibacterial. Therefore, exploration of langsat fruit as an antibacterial is needed. The purpose of this study was to determine the antibacterial activity of langsat fruit seeds against Staphylococus aureus and Klebsiella pneumoniae using the disc method and the well method. Langsat fruit seed powder was macerated using the maceration method with n-hexane solvent and tested for antibacterial activity. Inhibition of the n-hexane extract of langsat fruit seeds showed the largest clear zone diameter value given by the lowest concentration of 10% by the disc and sumurun method on the Staphylococus aureus and Klebsiella pneumoniaes bacteria 13.6 mm; 12.6 mm; 13 mm; and 14.6 mm. This shows that the n-hexane extract of langsat fruit seeds has strong antibacterial activity against Staphylococus aureus and Klebsiella pneumonia bacteria both by the disc method and the well method.

 

Keywords: langsat fruit seeds, Klebsiella pneumoniae, disc, pitting method, Staphylococus aureus

 

 

ABSTRAK

Biji buah langsat (Lansium domesticum Corr) merupakan salah satu bagian tanaman yang telah dikenal sebagai antibakteri. Maka dari itu, eksplorasi buah langsat sebagai antibakteri sangat diperlukan. Tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri biji buah langsat terhadap bakteri Staphylococus aureus  dan Klebsiella pneumoniae menggunakan metode cakram dan metode sumuran. Serbuk biji buah langsat dimaserasi menggunakan metode maserasi dengan pelarut n-Heksan dan dilakukan uji aktivitas antibakteri. Daya hambat ekstrak n-Heksan biji buah langsat menunjukkan nilai diameter zona bening terbesar diberikan oleh konsentrasi terendah 10% dengan metode cakram (13,6 mm pada bakteri Staphylococus aureus dan 12,6 mm pada bakteri Klebsiella pneumoniae) dan metode sumuran (13 mm pada bakteri Staphylococus aureus dan 14,6 mm pada bakteri Klebsiella pneumoniae). Hal ini menunjukkan bahwa ekstrak n-Heksan biji buah langsat memiliki aktivitas antibakteri yang kuat terhadap bakteri Staphylococus aureus  dan Klebsiella pneumoniae baik dengan metode cakram maupun metode sumuran.

 

Kata Kunci: biji buah langsat,Klebsiella pneumoniae, metode cakram, sumuran, Staphylococus aureus

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Published

2021-02-24

How to Cite

Nurhamidin, A. P., Fatimawali, F., & Antasionasti, I. (2021). UJI AKTIVITAS ANTIBAKTERI EKSTRAK N-HEKSAN BIJI BUAH LANGSAT (Lansium domesticum Corr) TERHADAP BAKTERI Staphylococus Aureus DAN Klebsiella Pneumoniae. PHARMACON, 10(1), 748–755. https://doi.org/10.35799/pha.10.2021.32772

Issue

Vol. 10 No. 1 (2021): PHARMACON

Section

Articles

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