Perbandingan Perubahan Kadar Gula Darah Sebelum Pembedahan, 30 Menit dan 60 Menit Saat Pembedahan dengan Anestesi Umum dan Anestesi Spinal

Abstract

Abstract: Anesthesia and surgery could cause stress response within the body that affects blood glucose level. This study was aimed to compare blood glucose levels at 30 minutes and 60 minutes during surgery using general anesthesia and spinal anesthesia. This as an observational prospective analytical stdy with a cross-sectional design performed on 12 patients gathered through consecutive sampling that fulfilled inclusion and exclusion criteria. The patients were divided into 2 groups: those undergoing surgery with general anesthesia and those with spinal anesthesia. Measurement of blood glucose level was done 3 times, 2 hours before premedication induction, 30 minutes and 60 minutes during surgery. Data were analyzed statistically by using the Shapiro-Wilk test, the T-independent test, and the Mann Whitney. The results showed that there was no significant difference between blood glucose level at 30 minutes during surgery using general anesthesia and spinal anesthesia (P = 0.23), however, there was a significant difference between blood glucose level at 60 minutes during surgery using general anesthesia and spinal anesthesia (P=0.03). Mean blood glucose level at30 minutes during surgery with general anesthesia was 103 mg/dl and at 60 minutes during surgery was 116.7 mg/dl, while mean blood glucose level at 30 minutes during surgery using spinal anesthesia was 93.50 mg/dl and at 60 minutes during surgery was 94.50 mg/dl. Conclusion: There was a significant difference in blood glucose level between general anesthesia and spinal anesthesia at 60 minutes during surgery.

Keywords: stress response, blood glucose level, general anesthesia, spinal anesthesia

Abstrak: Anestesi dan pembedahan dapat menyebabkan terjadinya suatu respon stres pada tubuh yang memengaruhi kadar gula darah. Penelitian ini bertujuan untuk membandingkan kadar gula darah 30 menit dan 60 menit saat pembedahan dengan anestesi umum dan anestesi spinal. Jenis penelitian ialah observasional analitik prospektif dengan desin potong lintang. Penelitian dilakukan terhadap 12 pasien yang didapatkan secara consecutive sampling dan memenuhi kriteria inklusi dan eksklusi, lalu dibagi menjadi 2 kelompok, yaitu kelompok yang menjalani pembedahan dengan anestesi umum dan kelompok yang menjalani menjalani pembedahan dengan anestesi spinal. Pengukuran kadar gula darah dilakukan 3 kali, yaitu 2 jam sebelum induksi premedikasi, serta 30 menit dan 60 menit saat pembedahan. Analisis statistik dilakukan dengan uji Shapiro-Wilk, uji T-Independen,, dan uji Mann Whitney. Hasil penelitian menunjukkan tidak terdapat perbedaan bermakna antara kadar gula darah 30 menit saat pembedahan dengan anestesi umum dan anestesi spinal (P=0,23) sedangkan pada 60 menit saat pembedahan menunjukkan adanya perbedaan bermakna antara kadar gula darah 60 menit saat pembedahan dengan anestesi umum dan anestesi spinal (P=0,03). Rerata kadar gula darah 30 menit saat pembedahan dengan anestesi umum yaitu 103 mg/dl dan 60 menit saat pembedahan yaitu 116,7 mg/dl, sedangkan rerata kadar gula darah 30 menit saat pembedahan dengan anestesi spinal yaitu 93,50 mg/dl dan 60 menit saat pembedahan yaitu 94,50 mg/dl. Simpulan: Perubahan kadar gula darah yang bermakna antara anestesi umum dan anestesi spinal terjadi pada 60 menit saat pembedahan.

Kata kunci: respon stres, kadar gula darah, anestesi umum, anestesi spinal