UJI AKTIVITAS ANTIJAMUR EKSTRAK ETANOL KULIT BATANG RAMBUTAN (Nephelium lappaceum L.) TERHADAP JAMUR Candida Albicans SECARA IN VITRO

Abstract

Fungal infections are often found in people in tropical countries including Indonesia because the
climate is hot and humid making it easier for mold growth. Empirically Rambutan bark
(Nepheliumlappaceum L.) used to treat ulcers caused by the fungus Candida albicans. The
experimentwasaimed to know the antifungal activity of ethanol extract of Rambutan bark against
Candida albicans and the effect of increasing concentrations of the Rambutan bark ethanol extract to
the antifungal activity. Rambutan bark ethanol extract obtained from the maceration process in
samples of wet and dry samples are prepared with concentrations of 10%, 20%, 40% and 80%.
Antifungal activity test was done by difussion method of well treatment to know the antifungal
effectiveness by observing the inhibition zone. The resultof the experiment that effective Rambutan
bark is used to inhibit the antifungal activity against Candida albicans. One way ANOVA test showed
that there were significant differences in inhibition zone diameters and followed by Duncan test with a
confidence level of 5% showed the highest inhibition zone diameters at a concentration of 80% and
ketoconazole(+)control.
Key words: Antifungals, Nepheliumlappaceum L., difussion method, Candida albicans