Instructions for Authors

GENERAL INFORMATION
1.Manuscripts must be original, have not been published previously in any scientific journal, that manuscripts are not being submitted for publication elsewhere, and will not be submitted to any media during the review process, unless the authors have officially withdrawn the manuscripts from Jurnal Ilmiah Sains. The statement must be stated in a statement of originality and copyright release form (Form A). Jurnal Ilmiah Sains uses Similarity Check to prevent any suspected plagiarism in the manuscripts.
2.Manuscripts submitted are research topics which have no conflict with bioethical research.
3.Manuscripts encompass research in the area of Mathematics and Natural Sciences from the following subject areas: Mathematics, Statistics, Computer Science, Physics, Chemistry, Biology.

MANUSCRIPT FILE
1.Manuscripts are written in English or Indonesian used standard scientific usage
2.Manuscripts should be prepared in Microsoft Word format, except for Graphs using Microsoft Excel program and Figures using JPEG or PDF format.
3.Manuscripts should be typed using Times New Roman (TNR) fonts at 12pt, except for the title size 14pt.
4.Manuscripts should be typed 1.15 spaced except for Title, Tables, Title of Graphs/Figures, and appendix typed single spaced. Manuscripts are prepared in A4 paper, with left margin is 3 cm, and right, top, botom margin respectively 2.5 cm. 
5.Manuscripts content should be arranged as the following order: Title, Name of the author(s) and their institutions, Abstract, Introduction, Research Methods, Results and Discussion, Conclusion, Declaration of  AI and AI-Assisted Technologies, Conflict of Interest, Author Contributions, Acknowledgement (if any), References.
6.Manuscripts are typed in one (1) column
7.Manuscripts and Form A should be submitted electronically through online system: https://ejournal.unsrat.ac.id/v3/index.php/jis

CONTENT OF MANUSCRIPTS
1. Title [TNR 14pt, bold, center] 
Title must be brief, clear, specific and informative which reflect the article content. The length of the title maximum 15 words in English and 20 words in Indonesian. Each word of the title should be started with capitalized letter.
2. Name of author(s)
The author's name consists of 2 words, namely first name and last name. Last names should not be abbreviated. If the author's name only consists of 1 word, then the last name is made the same as the first name [TNR 11pt, 1-line spacing]  .
3.Name of institution(s) 
Name of institutions where the research was conducted must be accompanied with full address including: Department/Study Program, University/Institution, city, country and adress. [TNR 11pt, 1-line spacing]
4. ABSTRACT 
The Abstract must be written in English and Indonesian as a single, concise, and self-contained paragraph of no more than 250 words for each language. It should clearly present the research background or problem, objective(s), methods, principal results, and conclusion, emphasizing the significance, novelty, or scientific contribution of the findings. The main results should be supported by specific quantitative data where applicable, rather than general statements. The conclusion must directly address the research objective(s) and reflect the findings without introducing unsupported claims. The Abstract must not contain citations, tables, figures, or unnecessary abbreviations. [TNR 12pt, 1 line spacing]  
5. Keywords
Provide 3–5 relevant and specific keywords or phrases that accurately represent the research content and enhance discoverability. Separate keywords using semicolons (;).[TNR 12pt, 1 line spacing]  
6. INTRODUCTION
The Introduction should provide a concise and well-structured background that leads directly to the central research question or the primary problem addressed in the study. The discussion should be supported by relevant, primary, and up-to-date scientific literature. References should predominantly consist of studies published within the last 1–10 years and directly related to the topic under investigation, with a minimum of five relevant references.
Authors should critically synthesize the existing literature to establish the scientific context of the study and clearly identify the unresolved issue or deficiency in current knowledge. The significance and rationale of the study should therefore be explicitly articulated through a clear statement of the analytical or knowledge gap (analysis gap statement).
In addition, the Introduction should clearly demonstrate the novelty and scholarly contribution of the present work by explaining how it differs from, extends, or improves upon previously published studies. This distinction should be expressed as a clear research gap statement that highlights the unique contribution, methodological advantage, conceptual advancement, or specific scientific value of the study.
The final sentence of the Introduction must explicitly state the objective(s) of the study in a concise and unambiguous manner, ensuring direct alignment with the research problem and the identified research. All in-text citations and reference lists must be generated using Mendeley reference management software and formatted consistently according to the APA 7th edition citation style. [TNR 12pt, 1.15 line spacing].
7. RESEARCH METHOD 
The Research Methods section should clearly and systematically describe the research design, location and period (where applicable), materials, instruments, data sources, experimental or computational procedures, and methods of data analysis. Sufficient methodological details must be provided to ensure transparency, reproducibility, and validity of the research findings.
Established methods must be supported by appropriate scientific references, while modifications or newly developed methods should be explicitly described and justified. Information on materials, equipment, software, sampling techniques, experimental conditions, and data collection procedures should be included where relevant.
Statistical or computational analyses must be appropriate to the research objectives, with clear descriptions of the analytical models, sample sizes, replication, statistical tests, significance levels, and software used, as applicable. Ethical approval and relevant research permits must be stated when required. The methods should be presented in a logical sequence, enabling other researchers to reproduce or independently verify the study. [TNR 12pt, 1.15 line spacing]. 
 8. RESULTS AND DISCUSSION
The Results and Discussion section should present the principal findings clearly, objectively, and systematically, following the research objectives. Results must be supported by appropriate tables, figures, or other evidence where necessary, without duplicating the same data across text, tables, and figures. Tables and figures must be numbered consecutively, provided with informative captions, and explicitly referred to in the text. Quantitative findings should include relevant measures of variability or uncertainty and statistical significance, where applicable.
The Discussion should critically interpret the findings rather than merely repeat the results. Authors must explain the scientific meaning of the findings, relate them to the research questions or hypotheses, and compare them with relevant and recent primary studies. Agreements or discrepancies with previous research should be analyzed using sound scientific reasoning, including plausible mechanisms or explanations where appropriate. The discussion should explicitly clarify the study’s novelty, scientific contribution, and implications for the relevant field.
Limitations, uncertainties, and the scope of interpretation should be acknowledged where relevant. Claims must be supported by the reported evidence and appropriate references; unsupported speculation and overgeneralization should be avoided. The section should maintain a logical connection among the research objectives, methods, findings, and conclusions. [TNR 12pt, 1.15 line spacing].
9. CONCLUSION
The Conclusion should be written concisely in a single paragraph, directly addressing the research objectives and highlighting the principal findings. It should provide a clear scientific interpretation of the results rather than merely repeat the data or statistical outcomes. Authors should emphasize the novelty, scientific contribution, and implications of the findings in relation to the identified research gap. Conclusions must be supported by the reported results, avoiding unsupported claims, excessive generalization, or the introduction of new data. Relevant limitations and recommendations for future research may be briefly included where appropriate. [TNR 12pt, 1.15 line spacing].
10. Declaration of  AI Tool Usage
Authors must disclose any substantive use of artificial intelligence (AI) tools in manuscript preparation, including the tool name and purpose of use. AI tools must not be listed as authors, and all AI-generated content must be critically reviewed and verified. Authors remain fully responsible for the accuracy, originality, and integrity of their work. The use of AI for research methods or data analysis must be clearly described in the Research Methods section. Fabrication or manipulation of scientific data, images, or references using AI is strictly prohibited.
AI Use Declaration: The authors used [AI TOOL] for [PURPOSE]. All AI-assisted content was reviewed and verified by the authors.
11. Conflict of Interest
Authors must disclose any financial or non-financial competing interests that could influence the research or its interpretation. All sources of research funding and the funders' roles, where applicable, must also be declared. The corresponding author is responsible for ensuring that all disclosures are complete and approved by all co-authors. If no competing interests exist, authors must state: "The authors declare no competing interests."
12. Author Contributions
All authors must clearly specify their individual contributions to the study in accordance with the CRediT (Contributor Roles Taxonomy). Contributions may include conceptualization, methodology, investigation, data analysis, writing, review, and editing. All authors must approve the final manuscript and accept responsibility for their contributions.
13. Acknowledgement (if any)
Acknowledgement (if any) to person(s) or institution(s) who help the experiment should be stated. Authors should also state the name and the number of the project. 
14. REFERENCES
a. The minimum number of references used is fifteen (15)
b. At least 80% of the references used come from journals, proceedings or theses and are up to date (last 10 years)
c. Writing references using APA Style (American Psychological Association Style)
d. Authors must use Mendeley reference management software to prepare citations and references in accordance with the journal's required citation style
e. It is not permitted to use secondary literature in citations, such as Hidayat (2018) in Miftah et al. (2019), and uses 'Anonymous' as a reference.
f. Examples of in-text reference citations: Hatidja (2025) or (Hatidja, 2025); Hatidja et al. (2025) or (Hatidja et al., 2025); Gultom & Lubis (2026) or (Gultom & Lubis, 2026).
g. Some examples of writing references are as follows:

Book
Hatidja, D. & Kekenusa, J.S. & Mongi, C.E.  (2024).  Metode Statistika.  CV. Patra Media Granfindo, Bandung.
Archie, G.E. (2003). The Electrical Resistivity Log as an Aid in Determining Some Reservoir Characteristics. SPE Reprint Series, 55, 9–16. DOI: 10.2118/942054-g
Journal
Hatidja, D., Patty, W., Kekenusa, J.S., Mandagi, S.V., Angmalisang, A.P., Budiman, J., Rogi Y.E.X. & Fauzy, A. (2025). Spatial and temporal analysis of scad fish (Decapterus spp.) catches in the Sulawesi Sea in relation to oceanography parameters using generalized additive models. Egyptian Journal of Aquatic Biology and Fisheries, 29(6), 979–1003. doi:10.21608/ejabf.2025.389185.5945.
Harlis, W.A., Saputri, D.Y., Malik, N., Septiana, A. & Resman, R. (2026). Toxicity of Copper (Cu) on Abnormalities and Mortality of Tilapia Fish (Oreochromis niloticus L.) Prolarvae. Jurnal Ilmiah Sains, 26(2), 105-114. https://doi.org/10.35799/jis.v26i2.67205.
Musavi, S. A., Bakhshi, H., & Khoobkar, Z. (2025). Biodiesel production from Chlorella sp. microalgae using new derived calcium methoxide-microalgae based catalyst. Fuel, 387(2025), 134459. https://doi.org/10.1016/j.fuel.2025.134459
Conference Proceedings
Titaley, J., Pinontoan, B., Hatidja, D., Lumingas, L., Manu, K. & Nanlohy, P.  (2024).  Variability of Sea Surface Temperature and Chlorophyll-a Distribution for Detecting Upwelling Area in Seram Sea Waters and Buru Island. AIP Conference  Proceeding, 3132, 060002-1–060002-6.  https://doi.org/10.1063/5.0211314.
Thesis/Disertation
Nely, F. (2007). Aktivitas Antioksidan Rempah Pasar dan Bubuk Rempah Pabrik dengan Metode Polifenol danUji Aom (Active Oxygen Method) [Skripsi]. Fakultas Teknologi Pertanian IPB, Bogor.
Haryanto, S.  (2019).  Analisis Mixed Geographically and Temporally Weighted Regression (MGTWR) PDRB Sektor Konstruksi di Jawa [Thesis]. Sekolah Pascasarjana, Institut Pertanian Bogor, Bogor.