Gambaran Ultrasonografi Ginjal pada Penderita Penyakit Ginjal Kronis dengan Diabetes Melitus di RSUP Prof. Dr. R. D. Kandou Periode Juli 2022 hingga Juli 2023
DOI:
https://doi.org/10.35790/msj.v7i1.53483Abstract
Abstract: Chronic kidney disease (CKD) occurs due to a long-lasting and irreversible decline in kidney function. This disease has a close relationship with diabetes mellitus (DM). Diabetic patients tend to experience microvascular complications, namely diabetic nephropathy which is the main cause of CKD. This study aimed to obtain the description of renal ultrasound in CKD patients with DM at Prof. Dr. R. D. Kandou Hospital from July 2022 to July 2023. This was a descriptive and retrospective study with a cross sectional design using proportional random sampling. The results obtained 68 samples of CKD patients with DM, dominated by females (57.4%), age group >65 years (32.4%), and had hemodialysis treatment (54.4%). The majority of CKD patients with DM were at level 2 severity based on the results of kidney ultrasound examination, where many had normal kidney size, increased parenchymal echogenicity, normal cortex thickness, clear echo cortex and medulla boundaries, normal pelvicalyceal system, and cysts as well as stones. In conclusion, the majority of chronic kidney disease patients with diabetes mellitus are females, aged over 65 years, have hemodialysis treatment, and are at level 2 severity.
Keywords: renal ultrasound; chronic kidney disease; diabetes mellitus
Abstrak: Penyakit ginjal kronis (PGK) terjadi karena penurunan fungsi ginjal yang berlangsung lama dan bersifat ireversibel. Penyakit ginjal kronis memiliki hubungan erat dengan diabetes melitus (DM). Penyandang DM akan mengalami komplikasi mikrovaskular yaitu nefropati diabetik yang menjadi penyebab utama terjadinya PGK. Penelitian ini bertujuan untuk mengetahui gambaran ultrasonografi ginjal pada penderita PGK dengan DM di RSUP Prof. Dr. R. D. Kandou periode Juli 2022 hingga Juli 2023. Jenis penelitian ialah deskriptif retrospektif dengan desain potong lintang dengan menggunakan teknik proportional random sampling. Hasil penelitian mendapatkan 68 sampel penderita PGK dengan DM, didominasi oleh jenis kelamin perempuan (57,4%), usia >65 tahun (32,4%), dan melakukan perawatan hemodialisis (54,4%). Mayoritas penderita PGK dengan DM berada pada derajat keparahan tingkat 2 berdasarkan hasil pemeriksaan USG ginjal, dimana banyak ditemukan ukuran ginjal normal, ekogenisitas parenkim meningkat, ketebalan korteks normal, batas echo korteks dan medula jelas, sistem pelvicalyceal normal, terdapat kista dan batu. Simpulan penelitian ini ialah mayoritas penderita penyakit ginjal kronis dengan diabetes melitus mayoritas ialah perempuan, kelompok usia >65 tahun, melakukan perawatan hemodialisis, dan berada pada derajat keparahan tingkat 2.
Kata kunci: ultrasonografi ginjal; penyakit ginjal kronis; diabetes melitus
References
Setiati S, Alwi I, Sudoyo AW, K MS, Setiyohadi B, Syam AF. Ilmu Penyakit Dalam (6th ed). Jakarta: Interna Publishing; 2017.
Bikbov B, Purcell CA, Levey AS, Smith M, Abdoli A, Abebe M, et al. Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the global burden of disease study 2017. Lancet. 2020;395(102250):709-33. Available from: https://www.thelancet.com/ journals/lancet/article/PIIS0140-6736(20)30045-3/fulltext
Kementerian Kesehatan Republik Indonesia. Laporan Riskesdas tahun 2018. Jakarta; 2018.
World Health Organization (WHO). Diabetes [Internet]. 2023 [cited 2 August 2023]. Available from: https: //www.who.int/news-room/fact-sheets/detail/diabetes#:~:text=In%202014%2C%208.5%25%20 of%20adults,the%20age%20of%2070%20years.
Mcfarlane P, Cherney D, Gilbert RE, Senior P. Chronic kidney disease in diabetes. Can J Diabetes. 2018;44(1):201-9. Available from: https://www.canadianjournalofdiabetes.com/article/S1499-2671(17)30985-1/fulltext
Jovanovic D, Gasic B, Pavlovic S, Naumovic R. Correlation of kidney size with kidney function and anthropometric parameters in healthy subjects and patients with chronic kidney diseases. Renal Failure. 2013;35(6):896-900. Available from: https://www.tandfonline.com/doi/full/10.3109/ 0886022X.2013.794683
Gani NS, Ali RH, Paat B. Gambaran ultrasonografi ginjal pada penderita gagal ginjal kronik di bagian radiologi FK Unsrat/SMF radiologi RSUP Prof. Dr. R. D. Kandou Manado periode 1 April-30 September 2015. e-CliniC. 2017;5(2):133-6. Available from: https://ejournal.unsrat.ac.id/index. php/eclinic/article/view/17419
Delima, Tjitra E, Tana L, Halim FS, Ghani L, Siswoyo H, et al. Faktor risiko penyakit ginjal kronik: studi kasus control di empat rumah sakit di Jakarta tahun 2014. Buletin Penelitian Kesehatan. 2017;45 (1):17-26. Available from: https://www.neliti.com/id/publications/74905/faktor-risiko-penyakit-ginjal-kronik-studi-kasus-kontrol-di-empat-rumah-sakit-di
Taneva OS, Otovic NE, Taneva B. Prevalence of diabetes mellitus in patients with chronic kidney disease. Open Access Maced J Med Sci [Internet]. 2016;4(1):79-82. Available from: https://oamjms.eu/ index.php/mjms/article/view/oamjms.2016.019
Baroleh MJ, Ratag BT, Langi FLF. Faktor-faktor yang berhubungan dengan penyakit ginjal kronis pada pasien di instalasi rawat jalan rumah sakit umum Pancaran Kasih Manado. Kesmas [Internet]. 2019;8(7). Available from: https://ejournal.unsrat.ac.id/index.php/kesmas/article/view/27233
Shen Y, Cai R, Sun J, Dong X, Huang R, Tian S, et al. Diabetes mellitus as a risk factor for incident chronic kidney disease and end-stage renal disease in women compared with men: a systematic review and meta-analysis. Endocrine. 2017;55(1):66-76. Available from: https://pubmed.ncbi. nlm.nih.gov/27477292/
Giandalia A, Giuffrida AE, Gembillo G, Cucinotta D, Squadrito G, Santoro D. Gender differences in diabetic kidney disease: focus on hormonal, genetic and clinical factors. Int J Mol Sci. 2021;22(11):5808. Available from: https://www.mdpi.com/1422-0067/22/11/5808
Pralisa K, Dewi DAK, Ilmiawan MI. Gambaran etiologi penyakit ginjal kronik stadium V pada pasien rawat inap di RSUD Dokter Soedarso Pontianak tahun 2017-2018. Jurnal Cerebellum. 2020;6(3): 59-65. Available from: https://jurnal.untan.ac.id/index.php/JC/article/view/45308/75676588438
Budianto Y. Hubungan diabetes mellitus dengan kejadian gagal ginjal kronik di ruang hemodialisa RSUD Dr. H. Ibnu Sutowo Baturaja Kabupaten Ogan Komering Ulu. Cendekia Medika. 2017;2(2):88-93. Available from: https://jurnal.stikesalmaarif.ac.id/index.php/cendekia_medika/article/view/41
Cahyani AAAE, Prasetya D, Abadi MF, Prihatiningsih D. Gambaran diagnosis pasien pra-hemodialisa di RSUD Wangaya tahun 2020-2021. Jurnal Ilmiah Hospitality. 2022;11(1):661-6. Available from: https://stp-mataram.e-journal.id/JIH/article/view/1819
Bestari AW. Pengaruh dukungan keluarga dan status DM dengan kualitas hidup pasien hemodialisis. Jurnal Berkala Epidemiologi. 2016;4(2):200-12. Available from: https://e-journal.unair.ac.id/ JBE/article/view/2146
Christy J, Martadiani ED, Sitanggang FP. Gambaran ultrasonografi ginjal pada penyakit ginjal kronis di RSUP Sanglah Denpasar. Jurnal Medika Udayana. 2020;9(7):36–40. Available from: https://ojs.unud.ac.id/index.php/eum/article/view/62954/35996
Zhang WX, Zhang ZM, Cao BS, Zhou W. Sonographic measurement of renal size in patients undergoing chronic hemodialysis: Correlation with residual renal function. Exp Ther Med. 2014;7(5):1259-64. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991538/
Gareeballah A, Gameraddin M, Salih S, Tamboul J. Sonographic assessment of kidneys and associated abdominal findings in patients with renal parenchymal diseases. Int J Res Med Sci. 2017;5(3): 1048-52. Available from: https://www.msjonline.org/index.php/ijrms/article/view/1259/2606
Hoi S, Takata T, Sugihara T, Ida A, Ogawa M, Mae Y, et al. Predictive value of cortical thickness measured by ultrasonography for renal impairment: a longitudinal study in chronic kidney disease. J Clin Med. 2018;7(12):527. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306756/
Singh A, Gupta K, Chander R, Vira M. Sonographic grading of renal cortical echogenicity and raised serum creatinine in patients with chronic kidney disease. J Evolution Med Dent. 2016;5(38):2278-84. Available from: https://www.jemds.com/data_pdf/1_Arvinder_Singh.pdf
Siddappa J, Singla S, Al Ameen M, Rakshith S, Kumar N. Correlation of ultrasonographic parameters with serum creatinine in chronic kidney disease. J Clin Imaging Sci. 2013;3(1):28. Available from: https://pubmed.ncbi.nlm.nih.gov/24083065/
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Wiwi Bolong, Joan F. J. Timban, Alfa G. E. Y. Rondo
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
COPYRIGHT
Authors who publish with this journal agree to the following terms:
Authors hold their copyright and grant this journal the privilege of first publication, with the work simultaneously licensed under a Creative Commons Attribution License that permits others to impart the work with an acknowledgment of the work's origin and initial publication by this journal.
Authors can enter into separate or additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (for example, post it to an institutional repository or publish it in a book), with an acknowledgment of its underlying publication in this journal.
Authors are permitted and encouraged to post their work online (for example, in institutional repositories or on their website) as it can lead to productive exchanges, as well as earlier and greater citation of the published work (See The Effect of Open Access).