Gambaran Faktor yang Memengaruhi Tren Angka Kejadian dan Keparahan Demam Berdarah Dengue pada Anak di RSUP Prof. Dr. R. D. Kandou Manado Periode 2020-2022
DOI:
https://doi.org/10.35790/msj.v7i1.53689Abstract
Abstract: Dengue infection remains as a significant global health issue due to its rapid spread and increasing number of cases each year. Dengue hemorrhagic fever (DHF) and its severity, dengue shock syndrome (DSS), can be caused by various factors, namely the host, behavior, environment, vectors, health services, and agents. This study aimed to determine the factors that influenced the trend of incidence and severity of DHF at Prof. R. D. Kandou Hospital, Manado. This was a descriptive and analytical study with a cross sectional design. The statistical analysis showed a significant correlation with a negative direction between air temperature and DHF incidence rate (p = 0.029, r = -0.363). Air humidity and rainfall did not have a significant relationship with DHF incidence. Based on the place of residence, a significant association was found with the severity of DHF (p=<0.001, OR=234.103). No significant association was found between economic level and the severity of the disease. In conclusion, there are significant relationships between air temperature and the incidence of DHF, and between the place of residence and the severity of the disease. It is expected that the government and the community can include these factors as indicators in efforts to prevent and control DHF and its severity.
Keywords: dengue hemorrhagic fever; dengue shock syndrome; risk factors; children
Abstrak: Infeksi dengue masih menjadi salah satu isu kesehatan global yang signifikan oleh karena penyebarannya yang cepat serta peningkatan jumlah kasus tiap tahunnya. Demam berdarah dengue (DBD) dan keparahannya yakni dengue shock syndrome (DSS) dapat diakibatkan oleh berbagai faktor, yakni faktor pejamu, perilaku, lingkungan, vektor, pelayanan kesehatan, dan agen. Penelitian ini bertujuan untuk mengetahui gambaran dari faktor-faktor yang memengaruhi tren angka kejadian dan keparahan DBD di RSUP Prof. R. D. Kandou Manado. Jenis penelitian ialah analitik deskriptif dengan desain potong lintang. Hasil analisis menunjukkan adanya korelasi bermakna dengan arah negatif antara suhu udara dengan angka kejadian DBD (p=0,029; r=-0,363). Kelembaban udara dan curah hujan tidak memiliki hubungan bermakna terhadap angka kejadian DBD. Berdasarkan tempat tinggal, didapatkan hubungan bermakna dengan tingkat keparahan DBD (p=<0,001; OR=234,103). Tidak terdapat hubungan bermakna antara tingkat ekonomi dengan tingkat keparahan penyakit. Simpulan penelitian ini ialah terdapat hubungan bermakna antara suhu udara dengan kejadian DBD, dan antara tempat tinggal dengan tingkat keparahan penyakit. Diharapkan bagi pemerintah dan masyarakat dapat mengikutsertakan faktor-faktor tersebut sebagai indikator dalam upaya pencegahan maupun penanggulangan DBD serta keparahannya.
Kata kunci: demam berdarah dengue; dengue shock syndrome; faktor risiko; anak
References
World Health Organization. Dengue and severe dengue [Internet]. 2023 [cited 2023 Aug 22]. Available from: https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue
World Health Organization. Regional Office for South-East Asia. Comprehensive guidelines for prevention and control of dengue and dengue haemorrhagic fever. World Health Organization Regional Office for South-East Asia; 2011. 196 p.
Schaefer TJ, Panda PK, Wolford RW. Dengue Fever. BMJ Best Practice [Internet]. 2022 Nov 14 [cited 2023 Aug 20];5–6. Available from: https://www.ncbi.nlm.nih.gov/books/NBK430732/
Kementerian Kesehatan Republik Indonesia. DATA DBD INDONESIA. 2021.
Badan Pusat Statistik Provinsi Sulawesi Utara. Kasus Penyakit Menurut Kabupaten/Kota dan Jenis Penyakit di Provinsi Sulawesi Utara 2020-2021 [Internet]. 2022 [cited 2023 Aug 22]. Available from: https://sulut.bps.go.id/indicator/30/912/1/kasus-penyakit-menurut-kabupaten-kota-dan-jenis-penyakit-di-provinsi-sulawesi-utara.html
Elsevier Point of Care. Clinical Overview: Dengue Virus Infection [Internet]. 2023 [cited 2023 Aug 20]. Available from: https://www.clinicalkey.com/#!/content/clinical_overview/67-s2.0-bd7b 1824-4575-4ec3-83a7-d6cf25f81615#diagnosis-heading-8
Verhagen LM, de Groot R. Dengue in children. Journal of Infection. 2014 Nov;69:S77–86. Doi: 10.1016/j.jinf.2014.07.020
Wong JM, Adams LE, Durbin AP, Muñoz-Jordán JL, Poehling KA, Sánchez-González LM, et al. Dengue: a growing problem with new interventions. Pediatrics. 2022;149(6):e2021055522. Doi: 10.1542/ peds.2021-055522
Reiskind MH, Zarrabi AA. Is bigger really bigger? Differential responses to temperature in measures of body size of the mosquito, Aedes albopictus. J Insect Physiol. 2012;58(7):911–7. Doi: 10.1016/j.jinsphys.2012.04.006
Susilawaty A, Ekasari R, Widiastuty L, Wijaya DR, Arranury Z, Basri S. Climate factors and dengue fever occurrence in Makassar during period of 2011–2017. Gac Sanit. 2021;35:S408–12. Doi: 10.1016/J.GACETA.2021.10.063
Rubel M, Anwar C, Irfanuddin I, Irsan C, Amin R, Ghiffari A. Impact of climate variability and incidence on dengue hemorrhagic fever in Palembang City, South Sumatra, Indonesia. Open Access Maced J Med Sci. 2021;9(E):952–8. Doi: 10.3889/oamjms.2021.6853
Abdullah NAMH, Dom NC, Salleh SA, Salim H, Precha N. The association between dengue case and climate: a systematic review and meta-analysis. One Health. 2022;15:100452. Doi: 10.1016/ j.onehlt.2022.100452
Figueredo MB, Monteiro RLS, do Nascimento Silva A, de Araújo Fontoura JR, da Silva AR, Alves CAP. Analysis of the correlation between climatic variables and dengue cases in the city of Alagoinhas/BA. Sci Rep. 2023;13(1):7512. Doi: 10.1038/s41598-023-34349-8
Hasanah, Susanna D. Weather Implication for dengue fever in Jakarta, Indonesia 2008-2016. KnE Life Sciences. 2019;4(10):184. Doi: 10.18502/kls.v4i10.3719
Rocklöv J, Tozan Y. Climate change and the rising infectiousness of dengue. Emerg Top Life Sci. 2019;3(2):133–42. Doi: 10.1042/ETLS20180123
Dengue increase likely during rainy season: WHO warns [Internet]. [cited 2023 Dec 1]. Available from: https://www.who.int/westernpacific/news/item/11-06-2019-dengue-increase-likely-during-rainy-season-who-warns
Ogashawara I, Li L, Moreno‐Madriñán MJ. Spatial‐temporal assessment of environmental factors related to dengue outbreaks in São Paulo, Brazil. Geohealth. 2019;3(8):202–17. Doi: 10.1029/2019 GH000186
Hossain S, Islam MdM, Hasan MdA, Chowdhury PB, Easty IA, Tusar MdK, et al. Association of climate factors with dengue incidence in Bangladesh, Dhaka City: a count regression approach. Heliyon. 2023;9(5):e16053. Doi: 10.1016/j.heliyon.2023.e16053
Monintja TCN, Arsin AA, Syafar M, Amiruddin R. Relationship between rainfall and rainy days with dengue hemorrhagic fever incidence in Manado City, North Sulawesi, Indonesia. Open Access Maced J Med Sci. 2022;10(E):840–3. Doi: 10.3889/oamjms.2022.8897
Getachew D, Tekie H, Gebre-Michael T, Balkew M, Mesfin A. Breeding sites of Aedes aegypti: potential dengue vectors in Dire Dawa, East Ethiopia. Interdiscip Perspect Infect Dis. 2015;2015:1–8. Doi: 10.1155/2015/706276
Abiodun GJ, Maharaj R, Witbooi P, Okosun KO. Modelling the influence of temperature and rainfall on the population dynamics of Anopheles arabiensis. [cited 2023 Dec 1]. Malar J. 2016;15(1):1–15. Available from: https://malariajournal.biomedcentral.com/articles/10.1186/ s12936-016-1411-6
Ramadina N, Ardisasmita MN, Sujatmiko B. Geographic accessibility towards primary health care in Karawang District. Kesmas. 2021;16(3). Doi: 10.21109/ kesmas.v16i3.4352
Mulligan K, Dixon J, Joanna Sinn CL, Elliott SJ. Is dengue a disease of poverty? A systematic review. Pathog Glob Health. 2015;109(1):10–8. Doi: 10.1179/2047773214Y.0000000168
Frenk J, Moon S. Governance Challenges in Global Health. New England Journal of Medicine. 2013;368(10):936–42. Doi: 10.1056/NEJMra1109339
Christofferson RC, Mores CN. A role for vector control in dengue vaccine programs. Vaccine. 2015; 33(50):7069–74. Doi: 10.1016/j.vaccine.2015.09.114
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