Hubungan Kadar Gula Darah Puasa dengan Kadar Low Density Lipoprotein (LDL) pada Pasien Diabetes Melitus Tipe 2
DOI:
https://doi.org/10.35790/msj.v8i1.62195Keywords:
diabetes melitus tipe 2; gula darah puasa; low density lipoproteinAbstract
Abstract: Type 2 diabetes mellitus (T2DM) is a chronic and multisystem disease that has reached epidemic proportions and is prone to cardiovascular complications due to dyslipidemia. Lipid profile, especially LDL cholesterol level, plays an important role in evaluating the risk of T2DM. This study aimed to determine the relationship between fasting blood glucose (FBG) level and low-density lipoprotein (LDL) level in patients with T2DM at the ODSK Hospital, North Sulawesi Province. This was an observational and analytical study with a cross-sectional design. This study used secondary data from medical records of T2DM patients at the ODSK Hospital, North Sulawesi Province in the period July 2023 to July 2024. The results obtained 61 patients with T2DM as samples who met the inclusion and exclusion criteria. The Spearman-Rank correlation test analysis obtained a p-value of 0,435 for the relationship between FBG and LDL levels. In conclusion, there is no significant relationship between fasting blood glucose and low-density lipoprotein in type 2 diabetes mellitus patients.
Keywords: type 2 diabetes mellitus; fasting blood glucose; low density lipoprotein
Abstrak: Diabetes melitus tipe 2 (DMT2) merupakan penyakit kronis dan multisistem yang telah mencapai proporsi epidemik dan rentan terhadap komplikasi kardiovaskular akibat dislipidemia. Profil lipid, khususnya pengukuran kadar kolesterol LDL, berperan penting dalam mengevaluasi risiko DMT2. Penelitian ini bertujuan untuk mengetahui hubungan kadar gula darah puasa (GDP) dengan kadar low density lipoprotein (LDL) pada pasien DMT2 di RSUD ODSK Provinsi Sulawesi Utara. Penelitian ini menggunakan metode observasional analitik dengan desain potong lintang. Jenis penelitian ialah retrospektif dengan memanfaatkan data sekunder catatan rekam medis pasien DMT2 di RSUD ODSK Provinsi Sulawesi Utara pada periode Juli 2023–Juli 2024. Hasil penelitian mendapatkan 61 pasien DMT2 sebagai sampel penelitian yang memenuhi kriteria inklusi dan eksklusi. Hasil analisis uji korelasi Spearman-Rank terhadap hubungan antara kadar GDP dan LDL mendapatkan nilai p=0,435. Simpulan penelitian ini ialah tidak terdapat hubungan bermakna antara kadar gula darah puasa dengan kadar low density lipoprotein pada pasien diabetes melitus tipe 2.
Kata kunci: diabetes melitus tipe 2; gula darah puasa; low density lipoprotein
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