UJI KEPEKAAN BAKTERI YANG DIISOLASI DARI SPUTUM PASIEN PENDERITA BRONKITIS KRONIK YANG MENJALANI RAWAT JALAN DI RSUP PROF. DR. R. D. KANDOU MANADO TERHADAP ANTIBIOTIK AMPICILIN, ERITROMISIN, DAN CIPROFLOXACIN
DOI:
https://doi.org/10.35799/pha.4.2015.10202Abstract
UJI KEPEKAAN BAKTERI YANG DIISOLASI DARIÂ SPUTUM PASIEN PENDERITA BRONKITIS KRONIK YANG MENJALANI RAWAT JALAN DI RSUP PROF. DR. R. D. KANDOU MANADO TERHADAP ANTIBIOTIK AMPICILIN, ERITROMISIN, DAN CIPROFLOXACIN
Kezia Novita Baharutan1), Fatimawali1) dan Adeanne Wullur1)
1)Program Studi Farmasi FMIPA UNSRAT Manado, 95115
Â
Â
Â
ABSTRACT
Antibiotic use in hospitals for the treatment of chronic bronchitis due to the bacterial infection is still based on empirical experience without culture results and bacterial sensitivity test to antibiotics. It caused a lot of failure of therapy and widespread bacterial resistance to antibiotics. This study, aims to determine the types of bacteria that cause the infection in the sputum of patients with chronic bronchitis  in outpatient installation of Prof. Dr. R. D. Kandou Manado and test the sensitivity to antibiotics Ampicillin, Erythromycin and Ciprofloxacin. Bacteria isolated from three samples of sputum of patients with chronic bronchitis and identified using biochemical tests and gram stain. The Sensitivity test for bacteria use disc diffusion of antibiotics Ampicillin, Erythromycin and Ciprofloxacin. The result showed that there are 5 kinds of bacteria, namely Bacillus sp. (37,5%), Escherichia coli (25%), Klebsiella pneumoniae (12,5%), Salmonella (12,5%), and Bacteroides gracilis (12,5%) with the highest sensitivity is ciprofloxacin (62,5%) and the highest Resistance is Ampicillin (100%).
Â
Keywords: Chronic Bronchitis, Isolation of Bacteria, Bacterial Sensitivity Test.
Â
Â
Â
ABSTRAK
Pola penggunaan antibiotik di rumah sakit untuk pengobatan bronkitis kronik akibat infeksi bakteri masih berdasarkan pada pengalaman empirik tanpa hasil kultur dan tes sensitifitas bakteri terhadap antibiotik. Akibatnya banyak terjadi kegagalan terapi dan meluasnya resistensi bakteri terhadap antibiotik. Penelitian ini bertujuan untuk menentukan jenis bakteri penyebab infeksi dalam sputum pasien penderita bronkitis kronik yang menjalani rawat jalan di RSUP Prof. Dr. R. D. Kandou Manado dan menguji kepekaannya terhadap antibiotik Ampicilin, Eritromisin dan Ciprofloxacin. Bakteri di isolasi dari 3 sampel sputum pasien bronkitis kronik dan di identifikasi menggunakan uji biokimia dan pewarnaan gram. Uji Kepekaan bakteri menggunakan difusi cakram dari antibiotik Ampicilin, Eritromicin dan Ciprofloxacin. Hasilnya didapat 5 jenis bakteri, yaitu Bacillus sp. (37,5%), Escherichia coli (25%), Klebsiella pneumonia (12,5%), Salmonella (12,5%), dan Bacteroides gracilis (12,5%) dengan sensitifitas tertinggi Ciprofloxacin sebesar 62,5% dan Resisten tertinggi sebesar 100% oleh Ampicilin.
Â
Kata Kunci: Bronkitis Kronik, Isolasi Bakteri, Uji Kepekaan Bakteri
Â
Downloads
Published
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)