SKRINING FITOKIMIA DAN UJI TOKSISITAS EKSTRAK ETANOL DAUN LANGSAT (Lansium domesticum Corr) TERHADAP Larva Artemia salina Leach DENGAN METODE Brine Shrimp Lethality Test (BSLT)

Authors

  • Indriawati Yunus

DOI:

https://doi.org/10.35799/pha.7.2018.20449

Abstract

SKRINING FITOKIMIA DAN UJI TOKSISITAS EKSTRAK ETANOL DAUN LANGSAT (Lansium domesticum Corr) TERHADAP Larva Artemia salina Leach DENGAN METODE Brine Shrimp Lethality Test (BSLT)

Indriawati Yunus1), Widdhi Boddhi1), Edwin De Queljoe 1)
1)Program Studi Farmasi FMIPA UNSRAT Manado, 95115


ABSTRACT
Langsat (Lansium domesticum Corr) is one of indigenous Indonesian plants that have long been used in traditional medicine. Some parts of langsat widely used to treat various diseases that is one the skin of stems and fruit, among others as a worm medicine, fever medicine, diarrhea drugs, and also as an anti-cancer. Other parts of leafy plants such as leaves have not been utilized and known toxicity levels. This study aims to identify phytochemical compounds and determine the toxicity value of leaf extracts of ethanol to leaf Artemia salina Leach through toxicity test using BSLT (Brine Shrimp Lethality Test) method. The results showed that leaf extract langsat (Lansium domesticum) contain phenolic compounds, saponins, triterpenoids, and steroids. The results of this study indicate that the leaf extract of ethanol is toxic, this is indicated by LC50 <1000 μg / mL, with LC50 value of 32.713 μg / mL.
Keywords: Leaf Langsat, Phytochemical, Toxicity, BSLT, LC50

ABSTRAK
Langsat (Lansium domesticum Corr) merupakan salah satu tanaman asli Indonesia yang telah lama digunakan dalam pengobatan tradisional. Beberapa bagian dari langsat banyak dimanfaatkan untuk mengobati berbagai penyakit yaitu pada kulit batang dan buahnya, antara lain sebagai obat cacing, obat demam, obat diare, dan juga sebagai antikanker. Bagian lainnya pada tanaman langsat seperti daun belum dimanfaatkan dan diketahui kadar toksisitasnya. Penelitian ini bertujuan untuk mengidentifikasi senyawa fitokimia dan menentukan nilai toksisitas dari ekstrak etanol daun langsat terhadap udang Artemia salina Leach melalui uji toksisitas menggunakan metode BSLT (Brine Shrimp Lethality Test). Hasil penelitian menunjukkan bahwa ekstrak daun langsat (Lansium domesticum) mempunyai kandungan senyawa fenolik, saponin, triterpenoid, dan steroid. Hasil penelitian ini menunjukkan bahwa ekstrak etanol daun langsat bersifat toksik, hal ini ditandai dengan nilai LC50 < 1000 μg/mL, dengan nilai LC50 yaitu 32,713 μg/mL.
Kata kunci: Daun Langsat, Fitokimia, Toksisitas, BSLT, LC50

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Published

2018-07-01

How to Cite

Yunus, I. (2018). SKRINING FITOKIMIA DAN UJI TOKSISITAS EKSTRAK ETANOL DAUN LANGSAT (Lansium domesticum Corr) TERHADAP Larva Artemia salina Leach DENGAN METODE Brine Shrimp Lethality Test (BSLT). PHARMACON, 7(3). https://doi.org/10.35799/pha.7.2018.20449

Issue

Vol. 7 No. 3 (2018): Pharmacon

Section

Articles

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