PENYALUTAN BAKTERI ASAM LAKTAT MENGGUNAKAN NANOPARTIKEL KITOSAN

Authors

  • Gabriella Sumeisey
  • Stella D. Umboh
  • Trina E. Tallei

DOI:

https://doi.org/10.35799/pha.8.2019.29361

Abstract

ABSTRACT

 

The lactic acid bacteria (LAB) are bacteria which have large contribution to provide functional benefits for the human body as a probiotic. One of the conditions needed for a bacterium to be catagorized as probiotic, is to be tolerant to low pH. The encapsulation approach using chitosan nanoparticles is one of the methods to prevent damage and the amount of probiotic bacteria reduction when they are exposed to low pH. Chitosan is a natural polymer, biocompatible, biodegradable, and not toxic substance, and can form microencapsulation with cross-bonding with tripolyphosphate. Therefor, chitosan is suitable for encapsulation of lactic acid bacteria.

 

Keywords : Lactitc acid bacteria, chitosan, microencapsulation, viability, pH low

 

 

 

ABSTRAK

 

Bakteri asam laktat merupakan bakteri yang memiliki kontribusi besar dalam memberikan manfaat fungsional bagi tubuh manusia sebagai probiotik. Salah satu syarat yang dibutuhkan agar suatu bakteri dinyatakan sebagai probiotik yaitu toleransi terhadap pH rendah. Pendekatan penyalutan (enkapsulasi) nanopartikel kitosan merupakan salah satu metode untuk mencegah kerusakan dan berkurangnya jumlah bakteri probiotik ketikan terpapar pada pH rendah. Kitosan merupakan polimer alami, biokompatibel, biodegradable, tidak beracun, dan dapat membentuk ikatan silang dengan tripolifosfat, sehingga kitosan dapat digunakan sebagai matriks pada mikroenkapsulasi (penyalutan mikro) bakteri asam laktat.

 

Kata kunci : bakteri asam laktat, kitosan, mikroenkapsulasi, viabilitas, pH rendah

Downloads

Published

2019-11-28

How to Cite

Sumeisey, G., Umboh, S. D., & Tallei, T. E. (2019). PENYALUTAN BAKTERI ASAM LAKTAT MENGGUNAKAN NANOPARTIKEL KITOSAN. PHARMACON, 8(4), 843–850. https://doi.org/10.35799/pha.8.2019.29361

Issue

Vol. 8 No. 4 (2019): PHARMACON

Section

Articles

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)