ACUTE TOXICITY TEST OF ETANOL EXTRACT FROM MANGOSTEEN PERICARP (Garcinia mangostana L. ) AGAINST ARTEMIA SALINA LEACH LARVAE USING BRINE SHRIMP LETHALITY TEST (BST)

Authors

  • Fatimawali Fatimawali Universitas Sam Ratulangi

DOI:

https://doi.org/10.35799/pha.2.2013.3893

Abstract

The aim of this research is to determine acute toxicity potency of mangosteen pericarp extract using Brine Shrimp Lethality Test (BST). This research was an experimental research using Post Test Only Control Group Design, using 250 larvaes as test subject which were divided into 5 groups. Each group contains 10 larvaes and each group was done by 5 replications. The test componen was mangosteen pericarp extract that given through the media which contains larvae as the animal test. The extract final concentration in media which contains larvae were 1000, 500, 200, 100 and 0 ppm as negative control. The result is against larvae that died 24 hours after component test was given. Through the data, LC 50 value of etanol extract of mangosteen rind was analyzed. The result shows that mangosteen rind extract on the media could kill larvae of Artemia salina. Prohibit analyzes shows that mangosteen extract LC50 value of mangosteen pericarp extract was 418 ppm. So the administering of rind extract of mangosteen (Garcinia mangostana L.) had acute toxicity potential against Artemia salina Leach larvae according to BST method.

 

Keywords : Garcinia mangostana L. pericarp, brine shrimp lethality test, acute toxicity

Downloads

How to Cite

Fatimawali, F. (2013). ACUTE TOXICITY TEST OF ETANOL EXTRACT FROM MANGOSTEEN PERICARP (Garcinia mangostana L. ) AGAINST ARTEMIA SALINA LEACH LARVAE USING BRINE SHRIMP LETHALITY TEST (BST). PHARMACON, 2(1). https://doi.org/10.35799/pha.2.2013.3893

Issue

Vol. 2 No. 1 (2013): pharmacon

Section

Articles

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)