Testing of Bacterial Resistance in Urine of UTI Patients to Levofloxacin and Ciprofloxacin Antibiotics in Makassar Prodia Clinic Laboratory”

Authors

  • Asmawiah Rame Stikes Nasional Surakarta
  • Vector Stephen Dewangga

Keywords:

UTI, urine, urine culture, ciprofloxacin, levofloxacin

Abstract

ABSTRACT

Urinary tract infection (UTI) is a clinical condition due to the proliferation of microorganisms that cause inflammation in the urinary tract and cause bacteriuria. Bacterial resistance to antibiotics continues to change, so research is carried out on the level of resistance to certain antibiotics in order to facilitate the treatment of UTI. Urine culture examination includes culturing the suspect bacteria, identifying and testing the antibiotics ciprofloxacin and levofloxacin. This study uses a descriptive research design. The sample of this study was 27 samples taken from patients who had been diagnosed with UTI and underwent therapy from a doctor. The results of the study of bacteria causing UTI resistance to the antibiotic levofloxacin 41%, and to the antibiotic ciprofloxacin 44%. Streptococcus agalactiae bacteria were found to be antibiotic resistant to levofloxacin and ciprofloxacin 37.5%, Escherichia coli was found to be antibiotic resistant to levofloxacin and ciprofloxacin 50%, Staphylococcus aureus was to be antibiotic resistant to levofloxacin 0% and ciprofloxacin 25%, and to floxacin to the antibiotic floxacin 25%, to be antibiotic resistant to floxacin. Streptococcus pyeogenes was found to be 0% resistant to levofloxacin and ciprofloxacin antibiotics, and to Klebsiella oxytoca and Enterococcus faecalis were found to be 100% resistant.


Author Biography

Asmawiah Rame, Stikes Nasional Surakarta

Mahasiswa Ahli teknologi laboratorium medik

References

REFERENSI

CHROMargar TM. 2017 Orientation Chromogenic media focus on Urinary tract pathogens. From : http://www.chromagar.com

CLSI. 2020. Perfomance Standards for Antimicrobial Susceptibility Testing 30th ed. CLSI supplement M100 Wayne, PA: Clinical and Laboratory Standards Institute.

Davis NG, Silberman M. 2020. Bacterial Acute Prostatitis. StatPearls Publishing. From: https://www.ncbi.nlm.nih.gov/books/NBK459257/

Douglas-Moore, J.L. & Goddard, J. 2018. Current Best Practice in The Management of Cystitis and Pelvic Pain. Ther Adv Urol

EAU, European Association of Urology. 2015. Guidelines on Urological Infection. s.l.: s.n

Elliott T, Worthington T, Osman H, Gill M. 2013. Mikrobiologi Kedokteran & Infeksi Edisi 4. Jakarta : EGC

Fauci, A.S., Kasper, D.L. Hauser, S.L. et al, 2008. Harrison‟s Principles of Internal Medicine 17th ed. United States Of America : McGraw Hill.

Febrianto,A.W., Mukaddas,A., Faustine,I. 2013. Rasionalitas Penggunaan Antibiotik pada Pasien Infeksi Saluran Kemih (ISK) di Instalasi Rawat Inap RSUD Undata Palu. Palu :Prodi Farmasi, Uniersitas Tadulako. Online Jurnal of Natural Science Volume 2

Goldman JA, Kearns GL. 2011. Fluoroquinolone Use in Paediatrics: Focus on Safety and Place in Therapy. USA: Expert Committee on the Selection and Use of Essential Medicines

Gradwohl S. E. 2011. Urinary Tract Infection Guideline. USA : Michigan Medicine

Grabe. Dkk. 2015. Guideline on urological infection. Europian Association of Urology

Greenwood, D., Barer, M., Slack, R., & Irving, W. 2012. Medical Microbiology (Eighteenth).

Guerrant, R. L., Walker, D. H., & Weller, P. F. 2011. Tropical Infectious Diseases: Principles, Pathogens and Practice (third). Saunders Ltd.

_______ 2006. Anatomi Fisiologi untuk Mahasiswa Keperawatan. Jakarta : EGC

Toelle, N.N., Lenda, V. 2014. Identifikasi dan Karakteristik Staphylococcus Sp. dan Streptococcus Sp. dari Infeksi Ovarium Pada Ayam Petelur Komersial. Jakarta : Ilmu Ternak

TQA pusat, 2015. Instruksi Kerja Kultur Urin. Jakarta : TQA Prodia

WHO. 2013. About Urinary Tract Infection. World Health Organization, Geneva : Available from htto://www.who.int

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Published

2022-12-07

How to Cite

Rame, A., & Dewangga, V. S. (2022). Testing of Bacterial Resistance in Urine of UTI Patients to Levofloxacin and Ciprofloxacin Antibiotics in Makassar Prodia Clinic Laboratory”. PHARMACON, 11(3), 1591–1596. Retrieved from https://ejournal.unsrat.ac.id/v3/index.php/pharmacon/article/view/40986

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