Uji aktivitas antihiperurisemia ekstrak etanol daun salam (Sygium Polyanthum) pada tikus putih (Rattus Norvegicus)
DOI:
https://doi.org/10.35799/pha.12.2023.42183Abstract
MEIVITA ALFRIANI SAHENSOLAR . Uji aktivitas antihiperusrisemia ekstrak etanol daun salam (Syzgium Polyanthum) pada tikus putih (Rattus Norvegicus)dibawah bimbingan EDWIN DE QUELJOE sebagai ketua dan SURYA SUMANTRI sebagai anggota.
Daun salam memiliki kandungan kimia seperti minyak atsiri yang mengandung sitral, eugenol, tannin, dan flavonoida. Penelitian ini bertujuan untuk mengetahui adanya efek antihiperurisemia ekstrak etanol daun salam dengan 3 tingkatan dosis yaitu, 200mg, 400mg, dan 800mg. Perbandingan daun Salam sebanyak 5 kelompok yang terdiri dari 3 ekor tikus disetiap kelompok perlakuan, yaitu CMC 1% (kontrol negatif), Allopurinol 100mg (kontrol positif), ekstrak etanol daun salam dalam dosis 200mg, 400mg, dan 800 mg,yang diinduksi kalium oksonat. Pengamatan dilakukan selama 6 jam. Data diuji dengan menggunakan ANOVA (Analisis Of Variant) ,uji HOMOGENITAS (Test of Homogenity of Variance) dan dilanjutkan dengan uji LSD (Least Significant Different). Hasil uji statistik menunjukan bahwa Dari ketiga dosis, penurunan kadar asam urat terbaik terdapat pada dosis 400 mg.
Kata Kunci: Ekstrak Daun Salam (Syzgium Polyanthum) , Antihiperusemia
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