UJI EFEKTIVITAS EKSTRAK KULIT BUAH SALAK (Salacca zalacca (Gaertn.) Voss) TERHADAP PENURUNAN KADAR GULA DARAH TIKUS PUTIH JANTAN GALUR WISTAR (Rattus norvegicus L.) YANG DIINDUKSI SUKROSA

Authors

  • Muharli Qadri Kanon
  • Fatimawali Fatimawali
  • Widdhi Bodhi

DOI:

https://doi.org/10.35799/pha.1.2012.486

Abstract

This study aimed at finding out the effectivity of Salacca (Salacca zalacca [Gaertn]
Voss) rind extract on blood sugar decrease of white male wistar (Rattus norvegicus L.)
induced with sucrose. Completely randomized design method was used in this experiment.
The subject of the experiment were 15 white male wistar which were divided into 3 (three)
groups namely negative control group, treatment group with the dose of 150 mg extract/kg
body weight, and positive control group using glibenclamide 0.45 mg/kg body weight. Data
obtained from the examination of the fasting blood sugar were 30 minutes after induction
with sucrose and at minute 15, 30, 60, and 120 after treatment was given. The data is
processed using ANOVA and LSD test to compare between the negative control group,
treatment, and a positive control. The analysis revealed a significant difference between
negative control and treatment, negative control and positive control, but did not show a
significant difference between treatment groups with the positive control. The conclusion of
this study is Salacca rind extract has an effect on blood sugar levels decrease of white male
wistar induced with sucrose.
Keywords: Salacca zalacca (Gaertn.) Voss, Salacca rind extract, blood sugar level, sucrose

Downloads

Published

2012-11-01

How to Cite

Kanon, M. Q., Fatimawali, F., & Bodhi, W. (2012). UJI EFEKTIVITAS EKSTRAK KULIT BUAH SALAK (Salacca zalacca (Gaertn.) Voss) TERHADAP PENURUNAN KADAR GULA DARAH TIKUS PUTIH JANTAN GALUR WISTAR (Rattus norvegicus L.) YANG DIINDUKSI SUKROSA. PHARMACON, 1(2). https://doi.org/10.35799/pha.1.2012.486

Issue

Vol. 1 No. 2 (2012)

Section

Articles

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)