Description of SGOT and SGPT Levels in Pregnant Women with Confirmed COVID-19

Authors

  • Clara V. I. Ponto Universitas Sam Ratulangi
  • Glady I. Rambert Universitas Sam Ratulangi
  • Mayer F. Wowor Universitas Sam Ratulangi

DOI:

https://doi.org/10.35790/msj.v3i2.37836

Abstract

Abstract: Physiological changes that occur during pregnancy cause pregnant women to become more susceptible to be infected with SARS-CoV-2 that could cause liver disorders. This study aimed to determine the overview of serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic-pyruvic transaminase (SGPT) levels in pregnant women with COVID-19 This was a descriptive study with a retrospective approach using secondary data in the form of patient medical records at Prof. Dr. R. D. Kandou Hospital in the period of July-August 2021. The results showed that based on the SGOT level among the second trimester patients, 1 patient (50%) had an increased SGOT in the range of 27-54 U/L and 1 patient (50%) had normal SGOT levels (<27 U/L). Among the third trimester patients, 15 patients (31%) had increased SGOT in the range of 26-53 U/L, 9 patients (18%) with increased SGOT >52 U/L, and 25 patients (51%) had normal SGOT. Based on SGPT levels among the second trimester patients, both patients (100%) had normal SGPT (<35 U/L), while in the third trimester patients, 4 patients (8%) had increased SGPT in the range of 29-58 U/L, 4 patients (8%) had increased SGPT >58 U/L, and 41 patients (84%) had normal SGPT (<29 U/L). In conclusion, most of the patients had normal SGOT and SGPT levels. There were more patients with increased SGOT than those with increased SGPT.

Keywords: COVID-19; pregnant women; SGOT; SGPT

 

Abstrak: Perubahan fisiologis yang terjadi selama kehamilan menyebabkan wanita hamil lebih mudah terinfeksi SARS-CoV-2 dan mengalami gangguan pada hati. Penelitian ini bertujuan untuk mengetahui gambaran serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic-pyruvic transaminase (SGPT) pada wanita hamil terkonfirmasi COVID-19. Jenis penelitian ialah deskriptif dengan pendekatan retrospektif menggunakan data sekunder berupa rekam medik pasien di RSUP Prof. Dr. R. D. Kandou periode Juli-Agustus 2021. Hasil penelitian memperlihatkan distribusi nilai SGOT pada pasien trimester II, didapatkan 1 pasien (50%) mengalami peningkatan SGOT pada rentang 27-54 U/L dan 1 pasien (50%) memiliki nilai SGOT normal, yaitu <27 U/L. Pada pasien trimester III, terdapat 15 pasien (31%) yang mengalami peningkatan SGOT pada rentang 26-52 U/L, 9 pasien (18%) dengan peningkatan nilai SGOT >52 U/L, dan 25 pasien (51%) memiliki nilai SGOT normal, yaitu <26 U/L. Pada distribusi nilai SGPT pasien trimester II, kedua pasien (100%) memiliki nilai SGPT normal, yaitu <35 U/L, sedangkan pada pasien trimester III, terdapat 4 pasien (8%) yang mengalami peningkatan SGPT pada rentang 29-58 U/L, 4 pasien (8%) mengalami peningkatan SGPT >58 U/L, dan 41 pasien (84%) memiliki nilai SGPT normal, yaitu <29 U/L. Simpulan penelitian ini ialah sebagian besar pasien memiliki SGOT dan SGPT normal. Pasien yang mengalami peningkatan SGOT lebih banyak daripada pasien yang mengalami peningkatan SGPT.

Kata kunci: COVID-19; wanita hamil; SGOT; SGPT

Author Biographies

Clara V. I. Ponto, Universitas Sam Ratulangi

Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Sam Ratulangi Manado

Glady I. Rambert, Universitas Sam Ratulangi

Bagian Patologi Klinik Fakultas Kedokteran Universitas Sam Ratulangi Manado

Mayer F. Wowor, Universitas Sam Ratulangi

Bagian Patologi Klinik Fakultas Kedokteran Universitas Sam Ratulangi Manado

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Published

2022-02-13

How to Cite

Ponto, C. V. I., Rambert, G. I., & Wowor, M. F. (2022). Description of SGOT and SGPT Levels in Pregnant Women with Confirmed COVID-19. Medical Scope Journal, 3(2), 134–142. https://doi.org/10.35790/msj.v3i2.37836