UJI EFEK ANTELMINTIK EKSTRAK ETANOL BIJI PINANG (ARECA CATECHU) TERHADAP CACING ASCARIS LUMBRICOIDES DAN ASCARIDIA GALLI SECARA IN VITRO

Abstract

Betel nut (Areca catechu) known as folks medicine that possess anthelmintic activity.
Anthelmintic were used to reduce or eliminate the worm in human or animal body. The aims
of this research were to find out anthelmintic activity of ethanol extract of betel nut against
Ascaris lumbricoides and Ascaridia galli, and to determine efective concentration of ethanol
extract of betel nut as an anthelmintic. This assay using ethanol extracts of betel nut with
concentration of 10%, 20%, and 30%. Mortality and paralysis percent of worms observed
every hour for 12 hours. Obtained data were analyzed by ANOVA. Regression analysis was
conducted to determine PC50 and LC50. The result show that ethanol extract of betel nut
possess an in vitro anthelmintic against Ascaris lumbricoides and Ascaridia galli. PC50 values
obtained in Ascaris lumbricoides was 27.12%, and LC50 values obtained in Ascaridia galli
was 27.11% on worm for 12 hours.
Keywords : Anthelmintic, ethanol extract of betel nut (Areca catechu), Ascaris lumbricoides,
Ascaridia galli