Faktor-faktor yang Memengaruhi Luaran Penanganan Gastroschisis

Authors

  • Michael Raktion Universitas Sam Ratulangi
  • Harsali F. Lampus Universitas Sam Ratulangi
  • Candy Candy Universitas Sam Ratulangi
  • Fredrik G. Langi Universitas Sam Ratulangi

DOI:

https://doi.org/10.35790/ecl.v11i3.46617

Abstract

Abstract: Gastroschisis is a congenital disorder in which the internal abdominal viscera protrudes through a defect in the anterior abdominal wall. Survival rates exceed 96% in high-income countries, but in low-income countries, mortality rates can reach >90%. This study aimed to determine the factors that influenced the outcome of gastroschisis treatment. This was an analytical study using SPSS ver. 22.0. The results obtained 18 infants with gastroschisis who met the criteria. All of the babies later developed sepsis and died. Characteristics of the sample were as follows: most gastroschisis diagnosis was confirmed after birth (83%), most cases recieved antenatal care from the midwife only (83%), delivery at the primary health facility (78%), baby was referred to the hospital without nasogastric tube and plastic wrap (50%)  and most babies had low risk (GPS≤1) (61%). Influencing significant factors found were the medical procedures performed before reffering to the length of hospital stay (p=0.007), length of parenteral nutrition (p=0.009), and duration to enteral feeding (p=0.005). In conlusion, medical procedures performed before reffering influence the outcome of gastroschisis treatment.

Keywords: gastroschisis; factors inflluencing the outcome of gastroschisis; Gastroschisis Prognostic Score

 

Abstrak: Gastroschisis adalah kelainan kongenital berupa protrusi visera internal abdominal melalui defek dinding abdomen anterior. Angka survival melebihi 96% di negara dengan pendapatan tinggi, namun di negara berpendapatan rendah, angka mortalitas dapat mencapai >90%. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang memengaruhi luaran penanganan gastroschisis. Penelitian ini menggunakan metode analitik dengan alat analisis SPSS ver. 22.0. Hasil penelitian mendapatkan 18 bayi dengan gastroschisis yang memenuhi kriteria. Setelah dilakukan operasi, seluruh bayi dirawat kemudian mengalami sepsis dan meninggal. Karakteristik sampel ialah diagnosis gastroschisis baru ditegakkan saat lahir (83%), ibu bayi memeriksakan kehamilannya pada bidan (83%), ibu melahirkan di faskes primer (78%), bayi dirujuk ke rumah sakit tanpa pemasangan NGT dan penutupan usus (50%), dan sebagian besar beresiko rendah (skor GPS ≤1) (61%). Faktor yang bermakna memengaruhi luaran penanganan gastroschisis ialah tindakan medis yang belum dilakukan sebelum merujuk terhadap lama rawatan rumah sakit (p=0,007), lama nutrisi parenteral (p=0,009), dan durasi hingga enteral feeding (p=0,005). Sinpulan penelitian ini ialah tindakan medis yang belum dilakukan sebelum merujuk merupakan faktor yang berpengaruh pada luaran penanganan bayi dengan gastroschisis.

Kata kunci: gastroschisis; faktor yang berperan terhadap luaran penanganan; Gastroschisis Prognostic Score

Author Biographies

Michael Raktion, Universitas Sam Ratulangi

Program Pendidikan Dokter Spesialis Bagian Ilmu Bedah Fakultas Kedokteran Universitas Sam Ratulangi, Manado, Indonesia

Harsali F. Lampus, Universitas Sam Ratulangi

Divisi Bedah anak Bagian Ilmu Bedah Fakultas Kedokteran Universitas Sam Ratulangi, Manado, Indonesia

Candy Candy, Universitas Sam Ratulangi

Divisi Bedah anak Bagian Ilmu Bedah Fakultas Kedokteran Universitas Sam Ratulangi, Manado, Indonesia

Fredrik G. Langi, Universitas Sam Ratulangi

Fakultas Kesehatan Masyarakat Universitas Sam Ratulangi, Manado, Indonesia

References

Al-Kaff A, MacDonald SC, Kent N, Burrows J, Skarsgard ED, Hutcheon JA, et al. Delivery planning for pregnancies with gastroschisis: findings from a prospective national registry. Am J Obstet Gynecol 2015;213(4): 557 e1-8.

Apfeld JC, Wren SM, Macheka N, Mbuwayesango BA, Bruzoni M, Sylvester KG, et al. Infant, maternal, and geographic factors influencing gastroschisis related mortality in Zimbabwe. Surgery. 2015;158(6):1475–80. Doi: 10.1016/j.surg.2015.04.037.

Bauseler A, Funke K, Mollers M, Hammer K, Steinhard J, Borowski M, et al. Outcome of fetuses with gastroschisis after modification of prenatal management strategies: prenatal management and outcome of gastroschisis. Arch Gynecol Obstet 2016;294(2)):239–43.

Bhat V, Moront M, Bhandari V. Gastroschisis: a state-of-the-art review. Children (Basel). 2020;7(12):302-8.

Cowan KN, Puligandla PS, Laberge JM, Skarsgard ED, Bouchard S, Yanchar N, et al. The gastroschisis prognostic score: reliable outcome prediction in gastroschisis. J Pediatr Surg. 2012;47(6):1111-7.

Fraser M, Utz M, Johnston T. Gastroschisis in Queensland 2008 to 2017. Queensland Health. 2018; 3(5):101-5.

Holland AJ, Walker K, Badawi N. Gastroschisis: an update. Pediatr Surg Int. 2010;26(9):871-8. Available from: https://doi.org/10.1007/s00383-010-2679-1.

Anderson JE, Galganski LA, Cheng Y, Stark RA, Saadai P, Stephenson JT, Shinjiro Hirose , Epidemiology of Gastroschisis: a population-based study in California from 1995 to 2012. J Pediatr Surg. 2018;53(12):2399-403. Doi: 10.1016/j.jpedsurg.2018.08.035.

Wissanji H, Puligandla PS. Risk stratification and outcome determinants in gastroschisis. Semin Pediatr Surg. 2018;27(5):300-3. Doi:10.1053/j.sempedsurg.2018.08

Oakes MC, Porto M, Chung JH. Advances in prenatal and perinatal diagnosis and management of gastroschisis. Semin Pediatr Surg. 2018;27(5):289-99. Available from: https://doi.org/10.1053/ j.sempedsurg.2018.08.006.

Puligandla PS, Baird R, Skarsgard ED, Emil S, Laberge JM, Canadian Pediatric Surgery Network (CAPSNet). Outcome prediction in gastroschisis: the gastroschisis prognostic score (GPS) revisited. J Pediatr Surg. 2017;52(5):718-21. Doi: 10.1016/j.jpedsurg.2017.01.017.

Shalaby A, Obeida A, Khairy D, Bahaaeldin K. Assessment of gastroschisis risk factors in Egypt. J Pediatr Surg. 2020;55(2):292-5. Doi:10.1016/j.jpedsurg.2019.10.02

Stevens P, Muller E, Becker P. Gastroschisis in a developing country: poor resuscitation is a more significant predictor of mortality than postnasal transfer time. S Afr J Surg. 2016;54(1):4–9, Available from: http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0038-23612016 000100002&lng= en&nrm=iso>.

Tassin M, Benachi A. Diagnosis of abdominal wall defects in the first trimester. Curr Opin Obstet Gynecol 2014;26((2)):104–9.

Thompson PJ, Walker K, Halliday R, Holland AJ, Trivedi A. Early enteral feeding following repair of gastroschisis is associated with shorter length of admission and better nutritional outcomes. J Clin Neonatol. 2017;6(4):231-5. Doi: 10.4103/jcn.JCN_50_17

Tullie LG, Bough GM, Shalaby A, Kiely EM, Curry JI, Pierro A, et al. Umbilical hernia following gastroschisis closure: a common event? Pediatric Surgery International. 2016;32(8): 811-4. Doi: 10.1007/s00383-016-3906-1

Wesonga AS, Fitzgerald TN, Kabuye R, Kirunda S, Langer M, kakembo N, et al. Gastroschisis in Uganda: opportunities for improved survival. J Pediatr Surg. 2016;51(11):1772–7. Doi: 10.1016/j.jpedsurg.2016.07.011.

Wright NJ, Langer M, Norman IC, Akhbari M, Wafford QE, Ade-Ajayi N, et al. Improving outcomes for neonates with gastroschisis in low-income and middle-income countries: a systematic review protocol. BMJ Paediatrics Open. 2018;2:e000392.

Downloads

Published

2023-08-19

How to Cite

Raktion, M., Lampus, H. F., Candy, C., & Langi, F. G. (2023). Faktor-faktor yang Memengaruhi Luaran Penanganan Gastroschisis. E-CliniC, 11(3), 330–338. https://doi.org/10.35790/ecl.v11i3.46617

Issue

Section

Articles