Giant Cell Tumor pada Ulna Distal: Laporan Kasus

Authors

  • Djarot Noersasongko Universitas Sam Ratulangi
  • Rangga Rawung Universitas Sam Ratulangi
  • Andriessanto C. Lengkong Universitas Sam Ratulangi
  • Haryanto Sunaryo Universitas Sam Ratulangi
  • Maurits R. Saleh Universitas Sam Ratulangi

DOI:

https://doi.org/10.35790/ecl.v11i3.46632

Abstract

Abstract: Giant cell tumor (GCT) in the distal end of ulna is extremely uncommon. We report a woman aged 53 tahun with a lump in the left wrist for three years that grew gradually and slowly. Physical examination of the left forearm revealed a tumor sized 8x9x10 cm, distinct border, hard in palpable without pain. X-ray of the left forearm showed a mass with distinct margin, regular edge, expansively invaded the epiphysis associated with thinning of cortex of distal ulna indicating a GCT in distal ulna. The aim of treatment in this case was to prevent recurrency and to keep the function of left forearm and hand. Patient was treated with tumor excision and fibular bone graft. Excision was performed after ulnar osteotomy until its clear margin. Fibular osteotomy 10 cm length was carried out followed by fibular bone graft to replace the excised ulna. Histopathological examination confirmed the diagnosis of a GCT. Patient was admitted for five days. Follow up after three months did not show any recurrency. Range of motion was within normal limit, and patient could do her daily activities. In conclusion, CGT in distal ulna treated with tumor excision until its clear margin followed by fibular bone graft showed satisfying result.

Kata kunci: giant cell tumor; fibular bone graft; tumor excision; primary bone tumor

 

Abstrak: Giant cell tumor (GCT) pada bagian distal ulna merupakan kasus langka. Kami melaporkan seorang perempuan berusia 53 tahun dengan benjolan di tangan kiri sejak tiga tahun yang membesar perlahan. Pada pemeriksaan fisik regio antebraki sinistra, didapatkan benjolan ukuran 8x9x10 cm, berbatas tegas, konsistensi keras, terfiksasi, tanpa disertai nyeri tekan. Rontgen manus sinistra memperlihatkan massa berbatas tegas, tepi reguler, mengenai epifisis ekspansif dengan penipisan korteks distal os ulna sinistra, kesan GCT distal os ulna sinistra. Tujuan terapi pada GCT untuk mencegah kekambuhan lokal dan menjaga fungsi anggota tubuh. Pasien diterapi dengan eksisi tumor dan fibular bone graft. Eksisi tumor dilakukan setelah osteotomi ulna hingga batas tulang yang sehat selanjutnya dilakukan osteotomi fibula sepanjang 10 cm dan dilakukan fibular bone graft menggantikan bagian ulna yang diangkat. Konfirmasi histopatologik sampel tumor menunjukkan interpretasi kesan giant cell tumor grade III.  Pasien dirawat selama lima hari. Hasil follow-up selama tiga bulan tidak menunjukan tanda-tanda rekurensi. Range of motion pasien saat kontrol dalam batas normal, dan pasien dapat mengerjakan aktivitas sehari-hari. Simpulan kasus ini ialah GCT pada tulang ulna dengan pilihan terapi eksisi tumor hingga batas tulang yang sehat, dilanjutkan dengan fibular bone graft berhasil memuaskan.

Kata kunci: giant cell tumor; fibular bone graft; eksisi tumor; tumor primer tulang

Author Biographies

Djarot Noersasongko, Universitas Sam Ratulangi

Divisi Ortopedi Departemen Ilmu Bedah, Fakultas Kedokteran Universitas Sam Ratulangi - RSUP Prof Dr. R. D. Kandou, Manado, Indonesia

Rangga Rawung, Universitas Sam Ratulangi

Divisi Ortopedi Departemen Ilmu Bedah Fakultas Kedokteran Universitas Sam Ratulangi, - RSUP Prof Dr. R. D. Kandou, Manado, Indonesia

Andriessanto C. Lengkong, Universitas Sam Ratulangi

Divisi Ortopedi Departemen Ilmu Bedah Fakultas Kedokteran Universitas Sam Ratulangi, - RSUP Prof Dr. R. D. Kandou, Manado, Indonesia

Haryanto Sunaryo, Universitas Sam Ratulangi

Divisi Ortopedi Departemen Ilmu Bedah Fakultas Kedokteran Universitas Sam Ratulangi, - RSUP Prof Dr. R. D. Kandou, Manado, Indonesia

Maurits R. Saleh, Universitas Sam Ratulangi

Program Pendidikan Dokter Spesialis Bagian Ilmu Bedah Fakultas Kedokteran Universitas Sam Ratulangi - RSUP Prof Dr. R. D. Kandou, Manado, Indonesia

References

Hartmann W, Harder D, Baumhoer D. Giant cell-rich tumors of bone. Surg Pathol. 2021;14(4):695–706.

Tsukamoto S, Mavrogenis AF, Kido A, Errani C. Current concepts in the treatment of giant cell tumors of bone. Cancers. 2021;13(15):3647.

Mavrogenis AF, Igoumenou VG, Megaloikonomos PD, Panagopoulos GN, Papagelopoulos PJ, Soucacos PN. Giant cell tumor of bone revisited. SICOT-J. 2017;3:54. Doi: 10.1051/sicotj/2017041.

Fandebnet S, Kotyade N, Nour ADM, O. N, Massar WB. Giant cell tumor of the wrist: rare location of the distal ulna. OJO. 2021;11(03):67–72.

Solichin I, Martika W, Wikanjaya R. Giant cell tumor of distal ulna treated using en-bloc resection combined with extensor carpi ulnaris and flexor carpi ulnaris tendon stabilization: a case report, International Journal of Surgery Case Reports (IJSCR). 2021;79:362-7. Available from: https://doi.org/10.1016/j.ijscr.2021.01.065.

Jamshidi K, Bahrabadi M, Bagherifard A, Mohamadpour M. Surgical treatment outcome of giant cell tumor of distal ulna: En bloc resection vs. curettage and bone graft. Med J Islam Repub Iran. 2018;32:44. Doi: 10.14196/mjiri.32.44. PMID: 30159295; PMCID: PMC6108277.

Vanni D, Pantalone A, Andreoli E, Caldora P, Salini V. Giant cell tumor of the distal ulna: a case report. J Med Case Rep. 2012;6:143. Doi: 10.1186/1752-1947-6-143.

Salunke AA, Shah J, Warikoo V, Chakraborty A, Pokharkar H, Chen Y, et al. Giant cell tumor of distal radius treated with ulnar translocation and wrist arthrodesis: What are the functional outcomes? J Orthop Surg (Hog Kong). 2017;25(1): 2309499016684972. Doi:10.1177/2309499016684972

Agrawal AC, Garg A, Choudhary R, Verma S, Dash RN. Giant cell tumor of the distal radius: wide resection, ulna translocation with wrist arthrodesis. Cureus. 2021;13(5):e15034. Doi: 10.7759/cureus.15034.

Minami A, Iwasaki N, Nishida K, Motomiya M, Yamada K, Momma D. Giant-cell tumor of the distal ulna treated by wide resection and ulnar support reconstruction: a case report. Case Rep Med. 2010:2010:871278. Doi: 10.1155/2010/871278.

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Published

2023-10-17

How to Cite

Noersasongko, D., Rawung, R., Lengkong, A. C., Sunaryo, H., & Saleh, M. R. (2023). Giant Cell Tumor pada Ulna Distal: Laporan Kasus. E-CliniC, 11(3), 364–368. https://doi.org/10.35790/ecl.v11i3.46632

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