Unequal Eye: A Case of Unilateral High Myopia and Anisometropia Amblyopia
DOI:
https://doi.org/10.35790/ecl.v13i1.58459Abstract
Abstract: Myopia, or nearsightedness, is a common eye condition. Unilateral myopia, where only one eye is nearsighted, poses unique challenges. The causes are complex, involving both genetics and environment. Treatment options include glasses, contact lenses, and surgery. We reported a case of a 13-year-old girl with unilateral high myopia and anisometropic amblyopia in her right eye. Despite no family history of myopia, the patient developed severe myopia in her right eye at the age of 7. A comprehensive ocular assessment was conducted, along with auxiliary tests. The patient was diagnosed with unilateral high myopia and anisometropia amblyopia. Treatment included a combination of spectacle correction, soft contact lenses, atropine eye drops, and patching therapy. Unilateral high myopia requires a thorough evaluation. The difference in eye length between the two eyes contributed to the patient's nearsightedness. Treatment options include glasses, contact lenses, orthokeratology, and surgical procedures. The patient received a personalized treatment plan with regular follow-up to monitor progress and assess treatment efficacy. In conclusion, this case underscores the importance of early detection and aggressive management of high myopia in pediatric patients to prevent further visual deterioration and potential complications.
Keywords: unilateral high myopia; amblyopia; anisometropia; management myopia
References
Holden BA, Fricke TR, Wilson DA, Jong M, Naidoo KS, Sankaridurg P, et al. Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050. Ophthalmology. 2016;123(5):1036-42. Doi: 10.1016/j.ophtha.2016.01.006.
Jiang Y, Xiao X, Sun W, Guo X, Li Z, Wang Y, et al. Clinical and genetic risk factors underlying severe consequence identified in 75 families with unilateral high myopia. J Transl Med. 2024;22(1):75. Doi: 10.1186/s12967-024-04886-5.
Martínez-Albert N, Bueno-Gimeno I, Gené-Sampedro A. Risk factors for myopia: a review. J Clin Med. 2023;12(18):6062. Doi: 10.3390/jcm12186062.
Freeman MI. Spectacles vs contact lenses in the correction of unilateral axial myopia. Arch Ophthalmol. 1992;110(2):180. Doi: 10.1001/archopht.1992.01080140036019.
Wang S, Zhang B, Liu Q, Zhou F, Chen Y, Xu J. Spectacle correction may affect refractive progression in children with unilateral myopic anisometropia: a retrospective study. Ophthalmic Physiol Opt. 2024;00(00):1–6. Available from: https://doi.org/10.1111/opo.13382.
Repka MX, Melia M, Eibschitz-Tsimhoni M, London R, Magoon E, Pediatric Eye Disease Investigator Group. The effect on refractive error of unilateral atropine as compared with patching for the treatment of amblyopia. J AAPOS. 2007;11(3):300-2. Doi: 10.1016/ j.jaapos.2006.09.017.
Hashem O, Sheha H. Ten-year outcomes of LASIK for pediatric myopic anisometropia. Clin Ophthalmol. 2022;16:4293-301. Doi: 10.2147/OPTH.S387302.
Swarbrick HA, Alharbi A, Lum E, Watt K. Changes in axial length and refractive error during overnight orthokeratology for myopia control. Invest Ophthalmol Vis Sci. 2011;52(14):2837-. Available from: https://iovs.arvojournals.org/article.aspx?articleid=2358251.
Baird PN, Saw SM, Lanca C, Guggenheim JA, Smith EL 3rd, Zhou X, et al. Myopia. Nat Rev Dis Primers. 2020;6(1):99. Doi: 10.1038/s41572-020-00223-2.
Chen Q, He J, Hu G, Xu X, Lv H, Yao Y, et al. Morphological characteristics and risk factors of myopic maculopathy in an older high myopia population—based on the new classification system (ATN). Am J Ophthalmol. 2019;208:356–66. Doi: 10.1016/j.ajo.2019.07.022.
Al Messabi SS, Dirani M, Mukhi-Marathe S. Adult onset unilateral high myopia in a female patient: a case report. Am J Ophthalmol Case Rep. 2020;20:100941. Doi: 10.1016/j.ajoc. 2020.100941.
Cooper J, Tkatchenko AV. A review of current concepts of the etiology and treatment of myopia. Eye Contact Lens. 2018;44(4):231–47. Doi: 10.1097/ICL.0000000000000499.
Varney K. Bringing unilateral high myopia into focus. Optometry & Visual Performance. 2018;6(3):130-4. Available from: https://www.ovpjournal.org/ovp-issue/volume-6--issue-3.
Weiss AH. Unilateral high myopia: optical components, associated factors, and visual outcomes. Br J Ophthalmol. 2003;87(8):1025-31. Doi: 10.1136/bjo.87.8.1025.
Subudhi P, Agarwal P. Myopia. [Updated 2023 Mar 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi. nlm.nih.gov/books/NBK580529/.
Arnon R, Rozen-Knisbacher I, Yahalomi T, Stanescu N, Niazov Y, Goldberg D, et al. Rise of the machines? Comparison of cycloplegic refraction using retinoscopy and the Retinomax K-Plus 5 in children. J Pediatr Ophthalmol Strabismus. 2022;59(6):380-7. Doi: 10.3928/01913913-20220712-01.
Tang SM, Chan RY, Bin LS, Rong SS, Lau HH, Lau WW, et al. Refractive errors and concomitant strabismus: a systematic review and meta-analysis. Sci Rep. 2016;6:35177. Doi: 10.1038/srep35177.
Clover J. Slit-Lamp Biomicroscopy. Cornea. 2018;37 (Suppl 1):S5-S6. Available from: https://journals.lww.com/corneajrnl/Fulltext/2018/37001/Slit_Lamp_Biomicroscopy.2.aspx.
Gellrich MM. A simple method for panretinal imaging with the slit lamp. Int Ophthalmol. 2016;36(6):775-80. Doi: 10.1007/s10792-016-0187-6.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Anne S. M. Umboh, Alberta Y. M. Tansil

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
COPYRIGHT
Authors who publish with this journal agree to the following terms:
Authors hold their copyright and grant this journal the privilege of first publication, with the work simultaneously licensed under a Creative Commons Attribution License that permits others to impart the work with an acknowledgment of the work's origin and initial publication by this journal.
Authors can enter into separate or additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (for example, post it to an institutional repository or publish it in a book), with an acknowledgment of its underlying publication in this journal.
Authors are permitted and encouraged to post their work online (for example, in institutional repositories or on their website) as it can lead to productive exchanges, as well as earlier and greater citation of the published work (See The Effect of Open Access).


