Faktor Risiko Terjadinya Enterokolitis Nekrotikan pada Neonatus
DOI:
https://doi.org/10.35790/ecl.v13i1.59445Abstract
Abstract: Necrotizing enterocolitis is inflammation of babies' digestive tract and the main cause of morbidity and mortality of premature neonates in the NICU. The exact etiology of necrotizing enterocolitis is not known so far. This study aimed to determine prematurity, formula feeding, sepsis, anemia, congenital heart disease and preeclampsia/eclampsia in mothers as risk factors for necrotizing enterocolitis in neonates and other risk factors that influence the incidence of necrotizing enterocolitis. This was a quantitative and analytical study with a cross sectional design. Sampling techniques were total sampling of necrotizing enterocolitis cases (38 patients) and executive sampling for control cases (38 patients) admitted to Prof. Dr. R. D. Kandou Hospital Manado using data of medical records. The results of the distribution table analysis and chi-square test showed that the risk factors analyzed that had p<0.05, namely prematurity (p<0.001), and sepsis (p<0.001). Other variables did not have significant relationships with the incidence of necrotizing enterocolitis (p>0.05), as follows: formula milk consumption (p>0.387), anemia (p>0.234), congenital heart disease (p>0.556), and mothers with preeclampsia/ eclampsia (p>0.556). In conclusion, prematurity and sepsis are risk factors for necrotizing enterocolitis in neonates at Prof. Dr. R. D. Kandou General Hospital, Manado.
Keywords: risk factors; necrotizing enterocolitis; neonates
Abstrak: Enterokolitis nekrotikan (EKN) merupakan peradangan pada usus saluran cerna bayi yang menjadi penyebab utama morbiditas dan mortalitas neonatus prematur di NICU. Tingkat kematian EKN makin tinggi pada bayi yang lebih kecil. Sampai saat ini etiologi yang jelas mengenai EKN belum diketahui secara pasti. Penelitian ini bertujuan untuk mengetahui prematur, pemberian susu formula, sepsis, anemia, penyakit jantung bawaan, dan preeklamsi/eklamsi pada ibu sebagai faktor risiko terjadinya EKN pada neonatus, dan mengetahui faktor risiko lain yang memengaruhi kejadian EKN. Jenis penelitian ialah analitik kuantitatif dengan desain potong lintang. Teknik sampling penelitian ialah total sampling pada kasus EKN 38 pasien dan executive sampling pada kontrol EKN 38 pasien yang dirawat di RSUP Prof. Dr. R. D. Kandou Manado melalui sumber data rekam medis. Hasil analisis tabel distribusi dan uji chi-square menunjukkan bahwa faktor risiko yang dianalisis mempunyai p<0,05 ialah faktor prematur (p<0,001), dan sepsis (p<0,001). Variabel lainnya tidak hubungan bermakna dengan kejadian EKN dengan nilai p>0,05 sebagai berikut: pemberian susu formula (p>0,387), anemia (p>0,234), penyakit jantung bawaan (p>0,556), dan preeklamsi/eklamsi pada ibu (p>0,556). Simpulan penelitian ini ialah prematur dan sepsis merupakan faktor risiko terjadinya enterokolitis nekrotikan pada neonatus di RSUP Prof. Dr. R. D. Kandou Manado.
Kata kunci: faktor risiko; enterokolitis nekrotikan; neonatus
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