Profil Pasien Inflammatory Bowel Disease di RSUP Prof. Dr. R. D. Kandou Manado Periode Tahun 2020 - 2022

Authors

  • Ni Nyoman E. Damiyanti Universitas Sam Ratulangi
  • Bradley J. Waleleng Universitas Sam Ratulangi
  • Octavianus R. H. Umboh Universitas Sam Ratulangi

DOI:

https://doi.org/10.35790/ecl.v13i1.60182

Abstract

Abstract: Inflammatory bowel disease (IBD) is a chronic idiopathic inflammation occurring in the digestive tract, divided into two types, namely ulcerative colitis (UC) and Crohn's disease (CD). This study aimed to obtain the profile of inflammatory bowel disease patients based on gender, age, and the most common clinical manifestations at the Gastroenterology Division of the Department of Internal Medicine, Prof. Dr. R. D. Kandou Manado Hospital from January 1, 2020, to December 31, 2022. This was a retrospective descriptive study using patients’ medical records from 2020 to 2022. The results showed that there were 86 IBD patients, with 49 CD cases and 37 UC cases; males (n=54) and females (n=32); age>45 years (65.1%), age 25-45 years (26.7%), and age<25 years (8.1%). Clinical presentations included abdominal pain, epigastric pain, liquid stools, weakness, and bloody stools. In conclusion, patients with inflammatory bowel disease were more prevalent in Chron disease than ulcerative colitis. Males were more common than females and the majority were over 45 years old. The most common clinical manifestation was abdominal pain.

Keywords: inflammatory bowel disease; Crohn's disease; ulcerative colitis

  

Abstrak: Penyakit radang usus merupakan radang idiopatik kronis yang terjadi pada saluran pencernaan yang dibagi atas dua jenis yaitu kolitis ulseratif (KU) dan penyakit Crohn (PC). Penelitian ini bertujuan untuk mengetahui gambaran pasien radang usus berdasarkan jenis kelamin, usia, dan gambaran klinis tersering di Divisi Gastroenterologi Ilmu Penyakit Dalam RSUP Prof. Dr. R. D. Kandou Manado periode 1 Januari 2020 - 31 Desember 2022. Jenis penelitian ialah deskriptif retrospektif menggunakan data sekunder pasien selama periode tahun 2020 - 2022. Hasil penelitian mendapatkan jumlah pasien radang usus (n=86), PC (n=49), dan KU (n=37); laki-laki (n=54) dan perempuan (n=32); usia >45 tahun (65,1%), usia 25-45 tahun (26,7%), dan usia <25 tahun (8,1%). Gambaran klinis nyeri perut, nyeri ulu hati, BAB cair, lemah badan, dan BAB darah. Simpulan penelitian ini ialah pasien radang usus lebih banyak terdapat pada penyakit Crohn daripada kolitis ulserosa, didominasi oleh laki-laki  dan usia >45 tahun. Gambaran klinis yang paling sering ditemukan ialah nyeri perut.

Kata kunci: penyakit radang usus; kolitis ulseratif; penyakit Crohn

Author Biographies

Ni Nyoman E. Damiyanti, Universitas Sam Ratulangi

Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Sam Ratulangi, Manado, Indonesia

Bradley J. Waleleng, Universitas Sam Ratulangi

Bagian Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Sam Ratulangi, Manado, Indonesia

Octavianus R. H. Umboh, Universitas Sam Ratulangi

Bagian Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Sam Ratulangi, Manado, Indonesia

References

Loscalzo J, Fauci AS, Kasper DL, Hauser S, Longo D, Jameson JL. Harrison’s Principles of Internal Medicine Vol. 1 (21st ed). McGraw Hill: 2022. p. 2469–90. Available from: https://accessmedicine.mhmedical. com/content.aspx?bookid=3095&sectionid=265395943

Feuerstein JD, Moss AC, Farraye FA. Ulcerative Colitis. Mayo Clin Proc [Internet]. 2019;94(7):1357–73. Available from: https://doi.org/10.1016/j.mayocp.2019.01.018

Lee Goldman, Kathleen A. Cooney. Goldman-Cecil Medicine Vol. 1 (27th ed). Poland: Elsevier; 2023. p. 941–50.

Salgado VCL, Luiz RR, Boéchat NLF, Leão IS, Do Carmo Schorr B, Parente JML, et al. Risk factors associated with inflammatory bowel disease: A multicenter case-control study in Brazil. World J Gastroenterol [Internet]. 2020;26(25):3611. Available from: https://doi.org/10.3748/wjg.v26.i25.3611

Ng SC, Kaplan GG, Tang W, Banerjee R, Adigopula B, Underwood FE, et al. Population density and risk of inflammatory bowel disease: a prospective population-based study in 13 countries or regions in Asia-Pacific. Am J Gastroenterol [Internet]. 2019;114(1):107–15. Doi: 10.1038/s41395-018-0233-2

Makmun D, Fauzi A, Maulahela H, Pribadi RR, editors. Konsensus Nasional Penatalaksanaan Inflammatory Bowel Disease [IBD] di Indonesia (Revisi 2019). Jakarta: Perkumpulan Gastrointestinal Indonesia (PGI); 2019.

Wing EJ, Schiffman. FJ. Cecil Essential of Medicine (10th ed). Philadelphia: Elsevier; 2022. p. 392–401.

Shah SC, Khalili H, Gower-Rousseau C, Olen O, Benchimol EI, Lynge E, et al. Sex-based differences in incidence of inflammatory bowel diseases-pooled analysis of population-based studies from Western countries. Gastroenterology2018;155(4):1079-89.e3. Doi: 10.1053/j.gastro.2018.06.043

Yang H, Zhou R, Bai X, Guo M, Ruan G, Wang L, et al. Trend and geographic variation in incidence and prevalence of inflammatory bowel disease in regions across China: A nationwide employee study between 2013 and 2016. Front Med (Lausanne) [Internet]. 2022 [cited 2024 Jan 9];9. Available from: https://doi.org/10.3389/fmed.2022.900251

Jain M, Venkataraman J. Inflammatory bowel disease: an Indian perspective. Indian Journal of Medical Research [Internet]. 2021;153(4):423. Available from: https://doi.org/10.4103/ijmr.ijmr_936_18

Sempere L, Bernabeu P, Cameo J, Gutiérrez A, García MG, García MF, et al. Gender biases and diagnostic delay in inflammatory bowel disease: multicenter observational study. Inflamm Bowel Dis [Internet]. 2023;29(12):1886-94. Doi: 10.1093/ibd/izad001

Wang R, Li Z, Liu S, Zhang D. Global, regional and national burden of inflammatory bowel disease in 204 countries and territories from 1990 to 2019: a systematic analysis based on the Global Burden of Disease Study 2019. BMJ Open 2023;13:e065186. doi:10.1136/ bmjopen-2022-065186.

Mosli MH, Alghamdi MK, Bokhary OA, Alzahrani MA, Takieddin SZ, Galai TA, et al. Inflammatory bowel disease in the elderly: a focus on disease characteristics and treatment patterns. Saudi Journal of Gastroenterology [Internet]. 2023;29(4):212–8. Available from: https://doi.org/10.4103/sjg.sjg_503_22

Severs M, Spekhorst LM, Mangen MJJ, Dijkstra G, Löwenberg M, Hoentjen F, et al. Sex-related differences in patients with inflammatory bowel disease: results of 2 prospective cohort studies. Inflamm Bowel Dis [Internet]. 2018;24(6):1298–306. Available from: https://doi.org/10.1093/ibd/izy004

Mokhtar NM, Nawawi KNM, Verasingam J, Zhiqin W, Sagap I, Azman ZAM, et al. A four-decade analysis of the incidence trends, sociodemographic and clinical characteristics of inflammatory bowel disease patients at single tertiary centre, Kuala Lumpur, Malaysia. BMC Public Health. 2019;19(Suppl 4):550. Doi: 10.1186/s12889-019-6858-2

Perler B, Ungaro R, Baird G, Mallette M, Bright R, Shah S, et al. Presenting symptoms in inflammatory bowel disease: descriptive analysis of a community-based inception cohort. BMC Gastroenterol. 2019;19(1):47. Doi: 10.1186/s12876-019-0963-7

Porter RJ, Kalla R, Ho GT. Ulcerative colitis: Recent advances in the understanding of disease pathogenesis. F1000Res. 2020; 2020 Apr 24:9:F1000 Faculty Rev-294

Mark Feldman, Lawrence S. Friedman, Lawrence J. Brandt. Sleisenger and Fordtran’s Gastrointestinal and Liver Disease Vol. 1 (11th ed). Gilaad G. Kaplan, Siew C.Ng, editors. Philadelphia: Elsevier; 2021. p. 1868.

Downloads

Published

2025-02-09

How to Cite

Damiyanti, N. N. E., Waleleng, B. J., & Umboh, O. R. H. (2025). Profil Pasien Inflammatory Bowel Disease di RSUP Prof. Dr. R. D. Kandou Manado Periode Tahun 2020 - 2022. E-CliniC, 13(1), 55–61. https://doi.org/10.35790/ecl.v13i1.60182

Issue

Section

Articles