Pengaruh Kafein dalam Kopi terhadap Kejadian Nyeri Kepala Primer pada Remaja
DOI:
https://doi.org/10.35790/ecl.v13i3.61333Abstract
Abstract: Primary headaches are one of the most common neurological disorders in the world, affecting 62% of adolescents worldwide. Coffee has been the most popular drink in the world for many years and has become a daily lifestyle for many people. Caffeine is a substance contained in coffee and this psychoactive substance is believed to be associated with primary headaches. This study aimed to evaluate the effect of caffeine in coffee on the incidence of primary headaches in adolescents. This was a systematic literature review using the meta-synthesis method. The results showed that low to moderate doses of caffeine tended to be safer, while higher doses (>200 mg/day) or irregular consumption could increase the risk of primary headache, and the combination of caffeine with anti-pain medication was more effective than a single therapy. In conclusion, there is a relationship between caffeine consumption in coffee and the incidence of primary headaches in adolescents, which can trigger or relieve the symptoms
Keywords: caffeine; coffee; primary headache; adolescents
Abstrak: Nyeri kepala primer menjadi salah satu gangguan neurologis yang paling umum di dunia. Kopi menjadi minuman paling populer di dunia selama bertahun-tahun dan telah menjadi gaya hidup sehari-hari bagi banyak orang. Kafein merupakan zat psikoaktif yang terkandung di dalam kopi, yang diyakini berhubungan dengan nyeri kepala primer. Penelitian ini bertujuan untuk mengetahui pengaruh kafein dalam kopi terhadap kejadian nyeri kepala primer pada remaja. Jenis penelitian ialah telaah literatur sistematis dengan metode meta-sintesis. Hasil penelitian mendapatkan bahwa kafein dosis rendah hingga sedang cenderung lebih aman, sementara dosis yang lebih tinggi (>200 mg/hari) atau konsumsi tidak teratur dapat meningkatkan risiko nyeri kepala primer. Kombinasi kafein dengan obat anti-nyeri lebih efektif dibanding terapi tunggal. Simpulan penelitian ini ialah terdapat hubungan antara konsumsi kafein dalam kopi dengan kejadian nyeri kepala primer pada remaja dimana mampu mencetus maupun meringankan gejala.
Kata kunci: kafein; kopi; nyeri kepala primer; remaja
References
Steiner TJ, Stovner LJ, Jensen R, Uluduz D, Katsarava Z. Migraine Remains second among the world’s causes of disability, and first among young women: findings from GBD2019. J Headache Pain. 2020;21(1):4–7. Doi:10.1186/s10194-020-01208-0
Mier RW, Dhadwal S. Primary headaches. Dent Clin North Am. 2018;62(4):611–28. Doi:10.1016/j.cden.2018.06.006
Almesned IS, Alqahtani NG, Alarif JA, Alsaawy TN, Agha S, Alhumaid MA. Prevalence of primary headache among medical students at King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia. J Fam Med Prim Care. 2018;7(6):1193–6. Doi:10.4103/jfmpc.jfmpc_240_18
Charles A. The pathophysiology of migraine: implications for clinical management. Lancet Neurol. 2018;17(2):174–82. Doi:10.1016/S1474-4422(17)30435-0
Zduńska A, Cegielska J, Zduński S, Domitrz I. Caffeine for headaches: Helpful or harmful? A brief review of the literature. Nutrients. 2023;15(14):3170. Doi:10.3390/nu15143170
ICO. World Coffee Statistics Database. 2024. Available from: https://ico.org/what-we-do/world-coffee-statistics-database/
Hammond D, Reid JL, Zukowski S. Adverse effects of caffeinated energy drinks among youth and young adults in Canada: a Web-based survey. Can Med Assoc. 2018;6(1):19-25. Doi:10.9778/cmajo.20160154
Eltyeb EE, Al-Makramani AA, Mustafa MM, Caffeine consumption and its potential health effects on Saudi adolescents in Jazan. Cureus. 2023;15(8):e44091. Doi:10.7759/cureus.44091
Bektaş Ö, Uğur C, Gençtürk ZB, Aysev A, Relationship of childhood headaches with preferences in leisure time activities, depression, anxiety and eating habits: A population-based, cross-sectional study. Cephalalgia. 2015;35(6):527-537. Doi:10.1177/0333102414547134
Kharaba Z, Sammani N, Ashour S, Caffeine consumption among various university students in the UAE, exploring the frequencies, different sources and reporting adverse effects and withdrawal symptoms. J Nutr Metab. 2022;2022:5762299. Doi:10.1155/2022/5762299
Dakhil FA, Aljohani WO, Almutairi GH, Identification of risk factors and adolescents’ beliefs about triggers for headaches: a cross-sectional study. International Journal of Medicine in Developing Countries. 2020;4(1):079-082. Doi:10.24911/IJMDC.51-1571232985
Khan N. Caffeinated beverages and energy drink: Pattern, awareness and health side effects among Omani university students. Biomed Res. 2019;30(1):113-21. Doi:10.35841/biomedicalresearch.30-19-014
Maqsood U, Zahra R, Latif MZ, Athar H, Caffeine consumption & perception of its effects amongst university students. Proceedings. 2020;34(4):46-51. Doi:10.47489/p000s344z770mc
Yang YM, Huh W, Jeong E, Lee JJ, Choi EJ. An analysis of consumption patterns of high-caffeinated energy drinks and adverse effects by surveys from students at middle and high schools in Korea. Yakhak Hoeji. 2014;58(6):387-96. Doi:10.17480/psk.2014.58.6.387
Maheshwari M. A Pan India cross sectional study among medical students on the therapeutic effects of coffee on tension type headache. Naučni časopis Urgent Med. 2023;29(2-3):38-49. Doi:10.5937/halo29-47700
Kumaat MA, Pertiwi JM, Mawuntu AHP. Hubungan antara migrain dan kafein. e-CliniC. 2021;9(2):334. Doi:10.35790/ecl.v9i2.32864
Souza JG De, Coso J Del, Fonseca FDS. Risk or benefit ? Side effects of caffeine supplementation in sport : a systematic review. Eur J Nutr. 2022;61(8):3823-34. Doi:10.1007/s00394-022-02874-3
Nowaczewska M, Wiciński M, Kaźmierczak W. The ambiguous role of caffeine in migraine headache: from trigger to treatment. Nutrients. 2020;12(8):2259. Doi:10.3390/nu12082259
Wattiez AS, Sowers LP, Russo AF. Calcitonin gene-related peptide (CGRP): Role in migraine pathophysiology and therapeutic targeting. Expert Opin Ther Targets. 2020;24(2):91–100. Doi:10.1080/14728222.2020.1724285
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