Profil Kasus Abses Leher Dalam dengan Diabetes Melitus
DOI:
https://doi.org/10.35790/ecl.v14i1.63725Keywords:
abses leher dalam; diabetes melitus; Klebsiella pneumonieAbstract
Abstract: Deep neck abscess (DNA) is a collection of pus in the deep neck space due to deep neck infection, this disease has rapid disease progression. In patients with diabetes mellitus (DM), there is a decrease in immune response, therefore, they are susceptible to infection. This study aimed to obtain the profile of DNA in patients with DM. This was a systematic literature review using the PICOS framework selection criteria. The results showed that based on the 10 literatures, the majoruty of patients were male, and the most frequent age groups were 44-60 years and 60-75 years. Tonsil infections, poor oral-hygiene, and odontogenic infection could increase the risk of having DNA. The most common pathogen to be found was Klebsiella pneumoniae. Patients with DM tended to have a longer length of stay compared to the patients who did not suffer from DM. In conclusion, deep neck abscess patients with DM tend to be found in males with older ages. The most commmon etiology and pathogen is odontogenic infection and Klebsiella pneumoniae. Diabetic patients with deep neck abscess tend to have longer length of stay compared to those without diabetes mellitus.
Keywords: deep neck abscess; diabetes mellitus; Klebsiella pneumoniae
Abstrak: Abses leher dalam (deep neck abscess/DNA) merupakan penumpukan pus di ruang leher dalam akibat infeksi leher dalam, yang memiliki progresivitas penyakit yang cepat. Pada pasien diabetes melitus (DM) terjadi penurunan respon imun sehingga pasien DM rentan terhadap infeksi. Penelitian ini bertujuan untuk memaparkan profil kasus DNA dengan DM. Jenis penelitian ialah systematic literature review dengan kriteria seleksi PICOS framework. Hasil penelitian mendapatkan 10 literatur. Mayoritas pasien DNA ialah ialah laki-laki, dan rentang usia 44-60 dan 60-75 tahun. Infeksi tonsil, kebersihan oral yang buruk, dan infeksi odontogenik dapat meningkatkan risiko DNA. Patogen yang sering menjadi penyebab infeksi ialah Klebsiella pneumoniae. Pasien DNA dengan DM cenderung memiliki waktu lama rawat inap yang lebih lama dibandingkan dengan pasien DNA yang tidak memiliki DM. Simpulan penelitian ini ialah pasien abses leher dalam dengan diabetes cenderung ditemukan pada jenis kelamin laki-laki dengan usia yang lebih tua. Etiologi dan patogen yang sering ditemukan ialah infeksi odontogenik dan Klebsiella pneumonie. Pasien abses leher dalam dengan diabetes cenderung memiliki waktu lama rawat inap yang lebih panjang dibandingkan dengan yang tanpa diabetes.
Kata kunci: abses leher dalam; diabetes melitus; Klebsiella pneumonie
References
1. Arliando MA, Adelien A, Utama DS. Prevalensi abses leher dalam di RSUP dr. Mohammad Hoesin Palembang periode 1 Januari 2012 – 31 Desember 2015. Maj Kedokt Sriwij. 2017;49(3):124–32. Available from: mks-fk.ejournal.unsri.ac.id/index.php/mks/article/download/90/88/90
2. McDowell RH, Hyser MJ. Neck Abscess. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 [cited 2022 Oct 10]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK459170/
3. Soepardi E, Iskandar N, Bashiruddin J, Restuti R, editors. Buku Ajar Ilmu Kesehatan Telinga, Hidung, Tenggorok, Kepala & Leher (6th ed). Jakarta: FKUI; 2017.
4. Almuqamam M, Gonzalez FJ, Kondamudi NP. Deep neck infections. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 [cited 2022 Oct 10]. Available from: http://www.ncbi.nlm.nih.gov/ books/NBK513262/
5. Brito TP, Hazboun IM, Fernandes FL, Bento LR, Zappelini CEM, Chone CT, et al. Deep neck abscesses: study of 101 cases. Braz J Otorhinolaryngol. 2017;83(3):341–8. Doi:10.1016/j.bjorl.2016.04.004
6. Luan CW, Liu CY, Yang YH, Tsai MS, Tsai YT, Hsu CM, et al. The pathogenic bacteria of deep neck infection in patients with type 1 diabetes, type 2 diabetes, and without diabetes from Chang Gung Research Database. Microorganisms. 2021;9(10):2059. Doi: 10.3390/microorganisms9102059
7. Sharma K, Das D, Joshi M, Barman D, Sarma AJ. Deep neck space infections-a study in diabetic population n a tertiary care centre. Indian J Otolaryngol Head Neck Surg. 2018;70(1):22–7. Doi: 10.1007/s12070-017-1196-0
8. Wu CL, Tsai MS, Lee TJ, Wang YT, Liu CY, Yang YH, et al. Type 2 diabetes mellitus increases peritonsillar abscess susceptibility: real-world evidence. Clin Exp Otorhinolaryngol. 2021;14(3):347–54. Doi: 10.21053/ceo.2020.02257.
9. Zheng L, Yang C, Kim E, Zhang W, Cai X, Jiang B, et al. The clinical features of severe multi-space infections of the head and neck in patients with diabetes mellitus compared to non-diabetic patients. Br J Oral Maxillofac Surg. 2012;50(8):757–61. Doi: 10.1016/j.bjoms.2012.01.019
10. Chang JS, Yoo KH, Yoon SH, Ha J, Jung S, Kook MS, et al. Odontogenic infection involving the secondary fascial space in diabetic and non-diabetic patients: a clinical comparative study. J Korean Assoc Oral Maxillofac Surg. 2013;39(4):175. Doi: 10.5125/jkaoms.2013.39.4.175
11. Chamora DR, Murdiyo MD, Maharani I. Association neutrophil lymphocyte ratio and therapy respons in submandibular abscess with and without diabetes. Oto Rhino Laryngol Indones. 2021;51(2):123-30. Available from: https://orli.or.id/index.php/orli/article/view/416
12. Chatterjee A, Chakraborty R. A comparative study of deep neck space infections (DNSI) in diabetic versus non-diabetic patients: our experience in a tertiary care centre. Int J Sci Res. 2021;X(II):32–4. Doi: 10.36106/ijsr/0301273
13. Ashokan S, Rajan KV, Santhi S. Deep neck space infections: comparison of outcomes between diabetic and non-diabetic patients. Int J Res Med Sci. 2021 Feb 25;9(3):711. Doi: 10.18203/2320-6012.ijrms20210502
14. Intan M, Surjotomo H. Gambaran pasien abses leher dalam dengan diabetes melitus dan tanpa diabetes melitus di Bagian IK THT-KL di RSUD Dr. Saiful Anwar Malang periode 1 Januari 2018 – 31 Desember 2019. Malang Otorhinolaryngol Head Neck Surg J. 2022;1(2):7–13. Available from: https:// moj.ub.ac.id/ index.php/moj/article/view/11
15. Arianto DR, Romdhoni AC. Pola kuman, hasil uji sensitifitas antibiotik dan komplikasi abses leher dalam di RSUD DR. Soetomo. Jurnal Ilmiah Kedokteran Wijaya Kusuma. 2019;8(1):88–98. Doi: 10.30742/jikw.v8i1.557
16. Fukai K, Takaesu Y, Maki Y. Gender differences in oral health behavior and general health habits in an adult population. Bull Tokyo Dent Coll. 1999;40(4):187–93. Doi: 10.2209/tdcpublication.40.187
17. Hidaka H, Yamaguchi T, Hasegawa J, Yano H, Kakuta R, Ozawa D, et al. Clinical and bacteriological influence of diabetes mellitus on deep neck infection: Systematic review and meta-analysis: influence of diabetes mellitus on deep neck infection. Head Neck. 2015;37(10):1536–46. Doi: 10.1002/hed.23776
18. Baglam T, Binnetoglu A, Yumusakhuylu AC, Gerin F, Demir B, Sari M. Predictive value of the neutrophil-to-lymphocyte ratio in patients with deep neck space infection secondary to acute bacterial tonsillitis. Int J Pediatr Otorhinolaryngol. 2015;79(9):1421–4. Doi: 10.1016/j.ijporl.2015.06.016
19. Klug TE, Greve T, Hentze M. Complications of peritonsillar abscess. Ann Clin Microbiol Antimicrob. 2020;19(1):32. Doi: 10.1186/s12941-020-00375-x
20. Biron VL, Kurien G, Dziegielewski P, Barber B, Seikaly H. Surgical vs ultrasound-guided drainage of deep neck space abscesses: a randomized controlled trial: surgical vs ultrasound drainage. J Otolaryngol - Head Neck Surg J Oto-Rhino-Laryngol Chir Cervico-Faciale. 2013;42(1):18. Doi: 10.1186/1916-0216-42-18
21. Wernly B, Lichtenauer M, Hoppe UC, Jung C. Hyperglycemia in septic patients: an essential stress survival response in all, a robust marker for risk stratification in some, to be messed with in none. J Thorac Dis. 2016;8(7):E621–4. Doi: 10.21037/jtd.2016.05.24
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