Gambaran Ultrasonografi Ginjal pada Penderita Penyakit Ginjal Kronis dengan Hiperurisemia di RSUP Prof. Dr. R. D. Kandou Periode Juli 2022 hingga Juli 2023
DOI:
https://doi.org/10.35790/msj.v6i2.53394Abstract
Abstract: Most studies identify hyperuricemia as an independent risk factor for chronic kidney disease (CKD). Radiologic examination, especially renal ultrasonography (USG), is an important examination to establish the diagnosis of this disease. This study aimed to investigate the overview of renal USG in CKD patients with hyperuricemia at Prof. Dr. R. D. Kandou Hospital from July 2022 to July 2023. This was a retrospective descriptive study with a cross sectional design using medical records of CKD patients with hyperuricemia who had renal USG performed on them at the Radiology Department of Prof. Dr. R. D. Kandou Hospital from July 2022 to July 2023 using proportional random sampling method. The results obtained 68 patients dominated by 56-65 years old (35.3%), male (57.4%), patients who did not undergo routine hemodialysis (69.1%), and 3th severity grade (41.9%). Renal USG characteristics were dominated by normal size (68.4%), increased parenchymal echogenicity (95.6%), normal cortex thickness (66.2%), blurred corticomedullary echogenicity differentiation (41.9%), and normal pelviocalyceal system (96.3%). In conclusion, CKD patients with hyperuricemia are mostly at the age of 56-65 years, male, at 3th severity grade, and do not undergo routine hemodialysis.
Keywords: chronic kidney disease; hyperuricemia; renal ultrasonography
Abstrak: Sebagian besar penelitian mengidentifikasi hiperurisemia sebagai faktor risiko independen terjadinya penyakit ginjal kronis (PGK). Pemeriksaan radiologis, terutama ultrasonografi (USG) ginjal, merupakan pemeriksaan penunjang yang penting untuk menegakkan diagnosis penyakit ini. Penelitian ini bertujuan untuk mengetahui gambaran USG ginjal pada penderita PGK dengan hiperurisemia di RSUP Prof. Dr. R. D. Kandou periode Juli 2022 hingga Juli 2023. Jenis penelitian ialah deskriptif retrospektif dengan desain potong lintang menggunakan rekam medis pasien PGK dengan hiperurisemia yang dilakukan pemeriksaan USG ginjal di RSUP Prof. Dr. R. D. Kandou pada Juli 2022 hingga Juli 2023. Pengambilan sampel menggunakan metode proportional random sampling. Hasil penelitian mendapatkan 68 pasien sebagai sampel penelitian yang didominasi oleh kelompok usia 56−65 tahun (35,3%), jenis kelamin laki-laki (57,4%), pasien yang tidak menjalani hemodialisis rutin (69,1%), dan derajat keparahan 3 (41,9%). Gambaran USG ginjal didominasi oleh ukuran normal (68,4%), ekogenisitas parenkim meningkat (95,6%), ketebalan korteks normal (66,2%), batas ekogenisitas korteks dan medula mengabur (41,9%), dan sistem pelviokalises normal (96,3%). Simpulan penelitian ini ialah penderita PGK dengan hiperurisemia sebagian besar berada pada usia 56-65 tahun, berjenis kelamin laki-laki, berada pada derajat keparahan 3, dan tidak menjalani hemodialisis rutin.
Kata kunci: hiperurisemia; penyakit ginjal kronis; ultrasonografi ginjal
References
Kampmann JD, Heaf JG, Mogensen CB, Mickley H, Wolff DL, Brandt F. Prevalence and incidence of chronic kidney disease stage 3–5 – results from KidDiCo. BMC Nephrol. 2023;24(1):17. Doi: 10.1186/s12882-023-03056-x
Bikbov B, Purcell CA, Levey AS, Smith M, Abdoli A, Abebe M, et al. Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2020;395(10225):709–33. Doi: 10.1016/S0140-6736(20)30045-3
Suriyong P, Ruengorn C, Shayakul C, Anantachoti P, Kanjanarat P. Prevalence of chronic kidney disease stages 3–5 in low- and middle-income countries in Asia: a systematic review and meta-analysis. PLoS One. 2022;17(2):e0264393. Doi: 10.1371/journal.pone.0264393
Kementerian Kesehatan Republik Indonesia. Laporan Nasional Riskesdas 2018. Jakarta; 2018. Available from: https://repository.badankebijakan.kemkes.go.id/id/eprint/3514/
Connelly K, Taal MW, Tangri N. Risk prediction in chronic kidney disease. In: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, editors. Brenner and Rector’s The Kidney (11th ed). Philadelphia: Elsevier; 2019. p. 640–65.
Piani F, Sasai F, Bjornstad P, Borghi C, Yoshimura A, Sanchez-Lozada LG, et al. Hyperuricemia and chronic kidney disease: to treat or not to treat. Braz J Nephrol. 2021;43(4):572–9. Doi: 10.1590/2175-8239-JBN-2020-U002
Krishnan E. Reduced glomerular function and prevalence of gout: NHANES 2009-10. PLoS One. 2012 ;7(11):e50046. Doi: 10.1371/journal.pone.0050046
Christy J, Dwi Martadiani E, Sitanggang FP. Gambaran ultrasonografi ginjal pada penyakit ginjal kronis di RSUP Sanglah Denpasar. Jurnal Medika Udayana. 2020;9(7):36–40. Doi: 10.24843/MU.2020. V09.i7.P07
Gani NSM, Ali RH, Paat B. Gambaran Ultrasonografi ginjal pada penderita gagal ginjal kronik di Bagian Radiologi FK Unsrat/SMF Radiologi RSUP Prof. Dr. R. D. Kandou Manado periode 1 April – 30 September 2015. e-Clinic. 2017;5(2):133–6. Doi: 10.35790/ecl.5.2.2017.17419
Rahmayati E, Sari G, Apriantoro HN, Prayogi DU, Irwan D, Restiyanti Y, et al. Gambaran morfologi USG ginjal dengan kreatinin tinggi pada kasus gagal ginjal kronik. In: KOCENIN Serial Konferensi. Indonesia: Webinar Nasional Pakar ke 4 Tahun 2021; 2021. p. 1.2.1-1.2.7.
Kodikara I, Gamage D, Nanayakkara G, Ilayperuma I. Renal ultrasound findings in chronic kidney disease – a single centre study from Hambantota district of Sri Lanka. Sri Lanka Journal of Medicine. 2019; 28(2):49. Doi: 10.4038/sljm.v28i2.129
Hall JE, Hall ME. Guyton and Hall Textbook of Medical Physiology (14th ed). Philadelphia: Elsevier; 2020. p. 321–30.
Hastuti VN, Murbawani EA, Wijayanti HS. Hubungan asupan protein total dan protein kedelai terhadap kadar asam urat dalam darah wanita menopause. J Nutr Coll. 2018;7(2):54–60. Doi: 10.14710/ jnc.v7i2.20823
Pranandari R, Supadmi W. Faktor risiko gagal ginjal kronik di unit hemodialisis RSUD Wates Kulon Progo. Majalah Farmaseutik. 2015;11(2):316–20. Doi: 10.22146/farmaseutik.v11i2.24120
Fajriansyah, Nisa M. Evaluasi tingkat kepatuhan penggunaan obat antihipertensi pada pasien penyakit ginjal kronik lanjut usia. Jurnal Ilmiah Manuntung. 2017;3(2):178–85. Doi: 10.51352/jim.v3i2.125
Abiyoga A. Faktor-faktor yang berhubungan dengan kejadian gout pada lansia di wilayah kerja puskesmas Situarja tahun 2014. Jurnal Darul Azhar. 2017;2(1):47–56. Available from: https://www. jurnal-kesehatan.id/ index.php/JDAB/article/view/24
Nasir M. Gambaran asam urat pada lansia di wilayah Kampung Selayar Kota Makassar. Jurnal Media Analis Kesehatan. 2017;8(2):78–82. Doi: 10.32382/mak.v8i2.842
Bakirci T, Sasak G, Ozturk S, Akcay S, Sezer S, Haberal M. Pleural effusion in long-term hemodialysis patients. Transplant Proc. 2007;39(4):889–91. Doi: 10.1016/j.transproceed.2007.02.020
Singh A, Gupta K, Chander R, Vira M. Sonographic grading of renal cortical echogenicity and raised serum creatinine in patients with chronic kidney disease. J Evol Med Dent Sci. 2016;5(38):2279–86. Doi: 10.14260/jemds/2016/530
Siddappa J, Singla S, Al Ameen M, Rakshith S, Kumar N. Correlation of ultrasonographic parameters with serum creatinine in chronic kidney disease. J Clin Imaging Sci. 2013;3(1):28. Doi: 10.4103/ 2156-7514.114809
Yamashita SR, Von Atzingen AC, Iared W, De Araújo BAS, Ammirati AL, Canziani MEF, et al. Value of renal cortical thickness as a predictor of renal function impairment in chronic renal disease patients. Radiol Bras. 2015;48(1):12–6. Doi: 10.1590/0100-3984.2014.0008
Zhang WX, Zhang ZM, Cao BS, Zhou W. Sonographic measurement of renal size in patients undergoing chronic hemodialysis: correlation with residual renal function. Exp Ther Med. 2014;7(5):1259–64. Doi: 10.3892/etm.2014.1560
Reddy GM, Reddy SS. Correlation renal cortical echogenicity with serum creatinine in patients with chronic kidney disease. Int J Radiol Diagn Imaging. 2020;3(3):99–102. Doi: 10.33545/26644436. 2020.v3.i3b.123
Murthy CM, Shettty BKK, Ganesh K, Monteiro FNP. Correlation of sonographic grading of renal cortical echogenicity with serum creatinine in patients with chronic kidney disease. Asian J Med Radiol Res. 2018;6(2):27–30. Available from: https://app.amanote.com/v4.0.66/research/note-taking? resourceIda=5o1Y03MBKQvf0BhisDyt
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