Pediatric Pleomorphic Adenoma of Parotid Gland: A Case Report

Authors

  • Vincent Suryoprabowo Universitas Sam Ratulangi
  • Harsali F. Lampus Universitas Sam Ratulangi
  • Candy Candy Universitas Sam Ratulangi
  • Denny Saleh Universitas Sam Ratulangi

DOI:

https://doi.org/10.35790/msj.v7i1.56144

Abstract

Abstract: Pleomorphic adenoma is a type of tumor that affects the parotid glands. It is also called a benign mixed tumor (BMT) because it has both epithelial and myoepithelial cells. This type of tumor is the most frequent parotid gland tumor, making up about 66% of all such tumors in parotid glands. We reported a case of 12-year-old male patient with a lump on his parotid gland, measured 7x3x3cm at Prof. Dr. R. D. Kandou Hospital Manado. CT Scan results of neck region of the patient revealed that there was a mass in the right side colli area and right frontal sinusitis A histopathological examination of the tumor tissue showed that it was encapsulated by connective tissue and composed of proliferating epithelial and myoepithelial tumor cells, some with clear nuclei, arranged in solid and microcystic patterns, and interspersed with fibromyxoid stroma. The patient was diagnosed as parotid gland adenoma, therefore, a parotidectomy was performed on him. He was discharged home and advised to return for a check-up one week later to remove the stitches. At the two-month follow-up visit, he was stable and did not require any additional therapy. In conclusion, a parotidectomy shows good result in the patient with parotid gland adenoma. However, due to the recurrence rate of parotid gland malignancies, several oncologists prefer to observe the patient periodically trough follow up at policlinic. Early detection and right management are required to achieve the best prognosis.

Keywords: pleomorphic adenoma; pediatric patient; parotid gland

Author Biographies

Vincent Suryoprabowo, Universitas Sam Ratulangi

Department of Surgery, Faculty of Medicine, Universitas Sam Ratulangi, Manado, Indonesia

Harsali F. Lampus, Universitas Sam Ratulangi

Division of Paediatric Surgery, Department of Surgery, Faculty of Medicine, Universitas Sam Ratulangi, Manado, Indonesia

Candy Candy, Universitas Sam Ratulangi

Division of Paediatric Surgery, Department of Surgery, Faculty of Medicine, Universitas Sam Ratulangi, Manado, Indonesia

Denny Saleh, Universitas Sam Ratulangi

Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, Universitas Sam Ratulangi, Manado, Indonesia

References

Mc Loughlin L, Gillanders SL, Smith S, Young O. The role of adjuvant radiotherapy in management of recurrent pleomorphic adenoma of the parotid gland: a systematic review. Eur Arch Otorhinolaryngol. 2019;276(2):283-95. Doi:10.1007/s00405-018-5205-z

Lee JH, Kang HJ, Yoo CW, Park WS, Ryu JS, Jung YS, et al. PLAG1, SOX10, and Myb expression in benign and malignant salivary gland neoplasms. J Pathol Transl Med. 2019;53(1):23-30. Doi: 10.4132/jptm.2018.10.12

To EW, Tsang WM, Tse GM. Pleomorphic adenoma of the lower lip: report of a case. J Oral Maxillofac Surg. 2002;60(6):684-6. Doi:10.1053/joms.2002.33120

Fu H, Wang J, Wang L, Zhang Z, He Y. Pleomorphic adenoma of the salivary glands in children and adolescents. J Pediatr Surg. 2012;47(4):715-9. Doi: 10.1016/j.jpedsurg.2011.10.067

Daniels JSM, Ali I, Al Bakri IM, Sumangala B. Pleomorphic adenoma of the palate in children and adolescents: a report of 2 cases and review of the literature. J Oral Maxillofac Surg. 2007;65(3):541-9. Doi: 10.1016/j.joms.2006.08.005

Infante-Cossio P, Gonzalez-Cardero E, Garcia-Perla-Garcia A, Montes-Latorre E, Gutierrez-Perez JL, Prats-Golczer VE. Complications after superficial parotidectomy for pleomorphic adenoma. Med Oral Patol Oral Cir Bucal. 2018;23(4) 485-92. Doi:10.4317/medoral.22386

Gontarz M, Wyszyńska-Pawelec G, Zapała J. Primary epithelial salivary gland tumours in children and adolescents. Int J Oral Maxillofac Surg. 2018;47(1):11-5. Doi: 10.1016/j.ijom.2017.06.004

Bentz BG, Hughes CA, Lüdemann JP, Maddalozzo J. Masses of the salivary gland region in children. Arch Otolaryngol Head Neck Surg. 2000;126(12):1435-9. Doi:10.1001/archotol.126.12.1435

Goyal G, Mehdi SA, Ganti AK. Salivary gland cancers: biology and systemic therapy. Oncology. 2015;29(10):773-9. Doi:10.1001/oncology.2015.10.012

Laishram RS, Kumar KA, Pukhrambam GD, Laishram S, Debnath K. Pattern of salivary gland tumors in Manipur, India: a 10-year study. South Asian J Cancer. 2013;2(4):250-3. Doi:10.4103/2278-330X.119886

Rodriguez KH, Vargas S, Robson C, Perez-Atayde A, Shamberger R, McGill TJ, et al. Pleomorphic adenoma of the parotid gland in children. Int J Pediatr Otorhinolaryngol. 2007;71(11):1717-23. Doi: 10.1016/j.ijporl.2007.07.019

Wang SJ, Eisele DW. Parotidectomy—Anatomical considerations. Clin Anat. 2012;25(1):12-8. Doi:10.1002/ca.21209

Davudov MM, Hasanova P. Pleomorphic adenoma of the parotid gland. J Pediatr Surg Case Rep. 2019;44:101186. Doi: 10.1016/j.epsc.2019.02.023

Rebours C, Couloigner V, Galmiche L, Casiraghi O, Badoual C, Boudjemaa S, et al. Pediatric salivary gland carcinomas: diagnostic and therapeutic management. Laryngoscope. 2017;127(1):140-7. Doi:10.1002/lary.26204

Mehra R, Cohen RB. New agents in the treatment for malignancies of the salivary and thyroid glands. Hematol Oncol Clin N Am. 2008;22(6):1279-95. Doi: 10.1016/j.hoc.2008.08.010

Abu-Ghanem AY, Mizrachi A, Popovtzer A, Abu-Ghanem N, Feinmesser R. Recurrent pleomorphic adenoma of the parotid gland: Institutional experience and review of the literature. J Surg Oncol. 2016;114(8):987-93. Doi:10.1002/jso.24392

Jain S, Hasan S, Vyas N, Shah N, Dalal S. Pleomorphic adenoma of the parotid gland: report of a case with review of literature. Ethiop J Health Sci. 2015;25(2):189-94. Doi:10.4314/ejhs.v25i2.13

Downloads

Published

2024-10-10

How to Cite

Suryoprabowo, V., Lampus, H. F., Candy, C., & Saleh, D. (2024). Pediatric Pleomorphic Adenoma of Parotid Gland: A Case Report. Medical Scope Journal, 7(1), 189–194. https://doi.org/10.35790/msj.v7i1.56144

Most read articles by the same author(s)