UJI AKTIVITAS ANTIBAKTERI EKSTRAK KULIT BUAH MANGGIS (Garcinia mangostana L.) TERHADAP BAKTERI Klebsiella pneumonlae

Authors

  • Brando Melkianus Program Studi Farmasi, Fakultas MIPA, Universitas Sam Ratulangi
  • Fatimawali Fatimawali Program Studi Farmasi, Fakultas MIPA, Universitas Sam Ratulangi
  • Sri Sudewi Program Studi Farmasi, Fakultas MIPA, Universitas Sam Ratulangi

DOI:

https://doi.org/10.35799/pha.8.2019.29241

Abstract

ABSTRACT

 

Research has been carried out on the Antibacterial Activity Test of Mangosteen (Garcinia mangostana L.) Fruit Bark Extract against Klebsiella pneumoniae bacteria. This study aims to determine the antibacterial activity of mangosteen peel extract using the diffusion method with positive control of Ciprofloxacin and negative control of aquades and the test solution used by mangosteen peel extract. The result showed differences in extract concentrations of 25% (6.66 mm) categorized as medium, extract concentractions of 50% (8.83 mm) categorized as medium, extract concentractions of 75% (9.16 mm) categorized as medium, and extract concentractions of 100% (10.16 mm) categorized as strong in influencing the inhibition of the growth of Klebsiella pneumoniae bacteria. The result of this study also showed that mangosteen peel extract (Garcinia mangostana L.), has a broad-spectrum bioactive compound which means it can inhibit the growth of Gram negative bacteria.

 

Keywords : Garcinia mangostana L, Klebsiella pneumoniae, Ciprofloxacin

 

 

ABSTRAK

 

Telah dilakukan penelitian tentang Uji Aktivitas Antibakteri Ekstrak Kulit Buah Manggis (Garcinia Mangostana L.) Terhadap Bakteri Klebsiella Pneumoniae. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri ekstrak kulit buah manggis menggunakan metode difusi agar dengan kontrol positif Ciprofloxacin dan kontrol negatif aquades serta larutan uji yang digunakan ekstrak kulit buah manggis. Hasil penelitian menunjukkan Perbedaan konsentrasi ekstrak 25% (6,66 mm) termasuk sedang, konsentrasi ekstrak 50% (8,83 mm) termasuk sedang, konsentrasi ekstrak 75% (9,16 mm) termasuk sedang, dan konsentrasi ekstrak 100% (10,16 mm) termasuk kuat dalam mempengaruhi penghambatan pertumbuhan bakteri Klebsiella Pneumoniae. Hasil penelitian ini juga menunjukan bahwa Ekstrak kulit buah manggis (Garcinia Mangostana L.), memiliki senyawa bioaktif dengan spektrum luas artinya dapat menghambat pertumbuhan bakteri Gram negatif.

 

Kata kunci : My Garcinia Mangostana L,  Klebsiella Pneunoniae, Ciprofloxacin

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Published

2019-02-28

How to Cite

Melkianus, B., Fatimawali, F., & Sudewi, S. (2019). UJI AKTIVITAS ANTIBAKTERI EKSTRAK KULIT BUAH MANGGIS (Garcinia mangostana L.) TERHADAP BAKTERI Klebsiella pneumonlae. PHARMACON, 8(1), 88–93. https://doi.org/10.35799/pha.8.2019.29241

Issue

Vol. 8 No. 1 (2019): PHARMACON

Section

Articles

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