EFEKTIFITAS PENYEMBUHAN LUKA BAKAR SALEP EKSTRAK ETANOL DAUN SOYOGIK (Sauraia Bracteosa DC) PADA TIKUS PUTIH JANTAN GALUR WISTAR (Rattus Norvegicus)

Authors

  • Dea Tumigolung
  • Max Runtuwene
  • Defny Wewengkang

DOI:

https://doi.org/10.35799/pha.8.2019.29303

Abstract

ABSTRACT

Soyogik leaves (Sauraia Bracteosa DC) contain flavonoids, phenolic, saponin and tannin. The contents in Soyogik Leaves is able to provide an effect to heal skin tissue damaged by burns. This study aims to formulate ethanol extract soyogik leaves ointment with concentration 20%, 25% and 30% to be tested for it’s effectiveness in healing burns. The method used is experimental laboratory. The wounds observation on the white rats back is done for 7 days by applying ointments 3 times a day. The results of the study showed that ethanol extract soyogik leaves with concentration 20%, 25%, and 30% have a healing effect on burns characterized by the decreasing burns diameter of white rats and the ointment with the fastest healing effect is the ointments with a 30% concentration.

Keywords: Soyogik (Sauraia bracteosa DC), ointment, burns, white rats (Rattus norvegicus)

ABSTRAK

Daun Soyogik (Sauraia Bracteosa DC) mengandung flavonoid, fenolik, saponin dan tanin. Kandungan yang terdapat dalam daun Soyogik mampu memberikan efek untuk menyembuhkan kulit yang mengalami kerusakan jaringan akibat luka bakar. Penelitian ini bertujuan untuk memformulasi sediaan salep ekstrak daun Soyogik dengan konsentrasi 20%, 25% dan 30% untuk diuji efektifitasnya terhadap penyembuhan luka bakar. Metode yang digunakan ialah eksperimental laboratorium. Pengamatan luka bakar pada punggung tikus putih dilakukan selama 7 hari dengan mengoleskan salep sebanyak 3 kali sehari. Hasil penelitian menunjukan salep ekstrak etanol dun Soyogik dengan konsentrasi 20%, 25% dan 30%  memiliki efek penyembuhan luka bakar diatandai dengan mengecilnya diameter luka bakar pada tikus dan efek penyembuhan yang paling cepat pada salep dengan konsentrasi 30% .

 

Kata kunci: Soyogik (Sauraia bracteosa DC), salep, luka bakar, tikus putih (Rattus norvegicus)

Downloads

Published

2019-05-28

How to Cite

Tumigolung, D., Runtuwene, M., & Wewengkang, D. (2019). EFEKTIFITAS PENYEMBUHAN LUKA BAKAR SALEP EKSTRAK ETANOL DAUN SOYOGIK (Sauraia Bracteosa DC) PADA TIKUS PUTIH JANTAN GALUR WISTAR (Rattus Norvegicus). PHARMACON, 8(2), 371–379. https://doi.org/10.35799/pha.8.2019.29303

Issue

Vol. 8 No. 2 (2019): PHARMACON

Section

Articles

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a  Creative Commons Attribution-NonCommercial 4.0 International License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

  2. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)