UJI AKTIVITAS ANTIJAMUR EKSTRAK ETANOL KULIT BATANG RAMBUTAN (Nephelium lappaceum L.) TERHADAP JAMUR Candida Albicans SECARA IN VITRO

Authors

  • Frendsiane Pangalinan
  • Novel Kojong
  • Paulina Yamlean

DOI:

https://doi.org/10.35799/pha.1.2012.439

Abstract

Fungal infections are often found in people in tropical countries including Indonesia because the
climate is hot and humid making it easier for mold growth. Empirically Rambutan bark
(Nepheliumlappaceum L.) used to treat ulcers caused by the fungus Candida albicans. The
experimentwasaimed to know the antifungal activity of ethanol extract of Rambutan bark against
Candida albicans and the effect of increasing concentrations of the Rambutan bark ethanol extract to
the antifungal activity. Rambutan bark ethanol extract obtained from the maceration process in
samples of wet and dry samples are prepared with concentrations of 10%, 20%, 40% and 80%.
Antifungal activity test was done by difussion method of well treatment to know the antifungal
effectiveness by observing the inhibition zone. The resultof the experiment that effective Rambutan
bark is used to inhibit the antifungal activity against Candida albicans. One way ANOVA test showed
that there were significant differences in inhibition zone diameters and followed by Duncan test with a
confidence level of 5% showed the highest inhibition zone diameters at a concentration of 80% and
ketoconazole(+)control.
Key words: Antifungals, Nepheliumlappaceum L., difussion method, Candida albicans

Downloads

Published

2012-08-01

How to Cite

Pangalinan, F., Kojong, N., & Yamlean, P. (2012). UJI AKTIVITAS ANTIJAMUR EKSTRAK ETANOL KULIT BATANG RAMBUTAN (Nephelium lappaceum L.) TERHADAP JAMUR Candida Albicans SECARA IN VITRO. PHARMACON, 1(1). https://doi.org/10.35799/pha.1.2012.439

Issue

Vol. 1 No. 1 (2012)

Section

Articles

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)