PENGARUH PERBEDAAN TIPE BASIS TERHADAP SIFAT FISIK SEDIAAN SALEP EKSTRAK ETANOL DAUN TAPAK KUDA (Ipomoea pes-caprae (L) Sweet ).

Authors

  • Nurlinda Wuri Ali

DOI:

https://doi.org/10.35799/pha.4.2015.8848

Abstract

PENGARUH PERBEDAAN TIPE BASIS TERHADAP SIFAT FISIK SEDIAAN SALEP EKSTRAK ETANOL DAUN TAPAK KUDA (Ipomoea pes-caprae (L) Sweet ).

Nurlinda Wuri Ali1), Paulina V. Y. Yamlean1), Novel  S. Kojong1)

1)Program Studi Farmasi Fakultas MIPA UNSRAT Manado

ABSTRACT

Tapak Kuda leaves contains the chemical contents such as alkaloid, flavonoid, tannin and steroid which is worked as antimicrobial and stimulate the growth of new cells in the wound. This research aims to test the effect of hydrocarbon ointment base type, absorption of ointment base, water leached ointment base, and Tapak Kuda leaves ethanol extract water soluble ointment base which involve organoleptic test, ph test, homogeneity test, and dispersive power test. Extraction was done by maceration method with 96% ethanol as the solvent. The result showed that four type of bases qualify the organoleptic test. The ointment pH qualify the skin pH (4,5-6,5). The Ointment has good homogeinity. In the dispersive power test, ointments with the type of hydrocarbons, absorption and water leached have the best results which is qualify the semisolid preparation parameters.

 

Keyword : Bases, Ointment, Tapak Kuda.

 

ABSTRAK

Daun tapak kuda Memiliki kandungan kimia alkaloid, flavonoid, tannin, steroid.  Yang bekerja sebagai antimikroba dan merangsang pertumbuhan sel baru pada luka. Penelitian ini bertujuan untuk menguji pengaruh tipe basis salep hidrokarbon, basis salep absorpsi, basis salep tercuci air dan basis salep larut air ekstrak etanol daun tapak kuda yang meliputi uji organoleptik, uji pH, uji homogenitas dan uji daya sebar. Ekstraksi dilakukan dengan cara maserasi dengan pelarut etanol 96 %. Berdasarkan  hasil penelitian menunjukkan ke empat tipe basis yang dibuat memenuhi syarat uji organoleptis. pH salep memenuhi parameter uji yang sama dengan pH kulit ( 4,5-6,5). Salep memiliki homogenitas yang baik. Pada uji daya sebar, salep dengan tipe hidrokarbon, absorpsi dan tercuci air memiliki hasil yang paling baik karena memenuhi parameter sediaan semisolid (5-7cm).

 

Kata kunci : Basis, Salep, Tapak Kuda

 

Downloads

Published

2015-08-06

How to Cite

Ali, N. W. (2015). PENGARUH PERBEDAAN TIPE BASIS TERHADAP SIFAT FISIK SEDIAAN SALEP EKSTRAK ETANOL DAUN TAPAK KUDA (Ipomoea pes-caprae (L) Sweet ). PHARMACON, 4(3), 110–116. https://doi.org/10.35799/pha.4.2015.8848

Issue

Vol. 4 No. 3 (2015): Pharmacon

Section

Articles

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)