Profil Nyeri pada Pasien Pascaoperasi Total Knee Arthroplasty di RSUP Prof. Dr. R. D. Kandou Manado
DOI:
https://doi.org/10.35790/ecl.v13i3.62662Abstract
Abstract: Total knee arthroplasty (TKA) is a definitive therapy for severe knee osteoarthritis. Postoperative acute pain is a major concern, as inadequate pain management can prolong rehabilitation and hospitalization. This study aimed to evaluate the use of analgesics and local anesthetic, and postoperative pain intensity in TKA patients at Prof. Dr. R. D. Kandou Hospital Manado from January 2023 to August 2024. This was a descriptive study aiming to observe the most commonly used analgesics and the pain intensity experienced by patients. The results showed that out of 64 patients who underwent TKA, single analgesic ketorolac was used in 4.92% of patients, while therapy with paracetamol, tramadol, and ketorolac was administered to 52.46% of patients, with mild pain being the most commonly reported complaint. The most frequently used local anesthetic was epidural morphine combined with paracetamol and ketorolac, accounting for 66.67% of the three patients who received local anesthetic therapy and reported mild pain. All patients received intravenous analgesics, with 4.92% also receiving oral administration. Postoperative pain management for TKA at Prof. Dr. R. D. Kandou Hospital Manado primarily utilized analgesics such as paracetamol, tramadol, and ketorolac, demonstrating mild pain intensity over the 72-hour recovery period. Similarly, local anesthetics like epidural morphine, combined with additional analgesics, yielded comparable effectiveness in TKA’s postoperative pain control.
Keywords: total knee arthoplasty; postoperative pain; analgesics; pain intesity
Abstrak: Total knee arthroplasty (TKA) merupakan terapi definitif untuk osteoartritis lutut berat. Nyeri akut pascaoperasi menjadi perhatian utama karena manajemen nyeri yang buruk dapat memperpanjang rehabilitasi dan rawat inap pasien. Penelitian ini mengkaji penggunaan analgetik, anestetik lokal dan intensitas nyeri pascaoeprasi TKA di RSUP Prof. Dr. R. D. Kandou Manado periode Januari 2023-Agustus 2024. Jenis penelitian ialah deksriptif dengan mengamati profil analgetik dan anestetik lokal yang paling banyak penggunaannya, serta intesitas nyeri yang dialami pasien. Hasil penelitian mendapatkan dari 64 pasien pascaoperasi TKA, penggunaan analgetik tunggal ketorolak tercatat pada 4,92% pasien, sementara terapi analgetik parasetamol, tramadol, dan ketorolak digunakan oleh 52,46% pasien dengan keluhan nyeri ringan yang paling sering dikeluhkan. Anestetik lokal yang paling sering digunakan ialah epidural morfin dengan tambahan analgetik parasetamol dan ketorolac, yaitu 66,67% dari tiga pasien yang mendapat terapi anestetik lokal dan keluhan nyeri ringan. Semua pasien menerima analgetik secara intravena; 4,92% di antaranya juga menerima melalui jalur peroral. Manajemen nyeri pascaoperasi TKA di RSUP Prof. Dr. R. D. Kandou Manado didominasi oleh penggunaan analgetik parasetamol, tramadol, dan ketorolak, yang menunjukkan intesitas nyeri ringan selama 72 jam perawatan. Anestetik lokal seperti epidural morfin dengan tambahan analgetik juga menunjukkan hasil serupa dalam kontrol nyeri pascaoperasi total knee arthroplasty.
Kata kunci: total knee arthroplasty; nyeri pascaoperasi; analgetik; intesitas nyeri
References
Li J, Ma Y, Xiao L. Postoperative pain management in total knee arthroplasty. Orthop Surg. 2019;11(5):755–61. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819170/
Steinmetz JD, Culbreth GT, Haile LM, Rafferty Q, Lo J, Fukutaki K, et al. Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the global burden of disease study 2021. The Lancet Rheumatology. 2023;5(9):e508–22. Available from: https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(23)00163-7/fulltext
Paladini A, Rawal N, Martínez MC, Trifa M, Montero AA, Pergolizzi JV, et al. Advances in the management of acute postsurgical pain: a review. Cureus. 2023;15(8):e42974 Available from: https://www. ncbi.nlm.nih.gov/pmc/articles/PMC10475855/
Lavand’homme PM, Kehlet H, Rawal N, Joshi GP. Pain management after total knee arthroplasty. Eur J Anaesthesiol. 2022;39(9):743–57. Doi: https://doi.org/10.1097/eja.0000000000001691
Suciati HW, Setiawati MCN. Gambaran penggunaan analgetika pada operasi orthopedi di Instalasi Bedah Sentral RSUD dr. Loekmono Hadi Kudus. Jurnal Ilmiah Manuntung. 2021;7(2):202–7. Available from: https://jom.unri.ac.id/index.php/JOMFDOK/article/view/15497
Ramadani L, Hidayat N. Gambaran penggunaan analgetik pada pasien rawatan intensif di RSUD Arifin Achmad Provinsi Riau periode Januari-Desember 2015. Jurnal Online Mahasiswa (JOM) Bidang Kedokteran. 2015;4(2):1–13. Available from: https://jom.unri.ac.id/index.php/JOMFDOK/article/view/15497
Barr J, Fraser GL, Puntillo K, Ely EW, Gélinas C, Dasta JF, et al. Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Crit Care Med. 2013;41(1):263–306. Available from: https://www.ncbi.nlm.nih.gov/pubmed/23269131/
Misiołek H, Cettler M, Woroń J, Wordliczek J, Dobrogowski J, Mayzner-Zawadzka E. et al. Anestezjologia Intensywna Terapia. 2014;46(4):221–44. Doi: https://doi.org/10.5603/ait.2014.0041
Asimin NF, Kumaat L, Lalenoh D. Perbandingan nyeri pasca seksio sesarea pada penderita yang diberikan ketorolak dan tramadol dengan petidin. e-CliniC. 2015;3(3):830-7. Doi: http://dx.doi.org/10.35790/ecl.3.3.2015.10593
Hilal-Dandan R, Brunton LL, Goodman LS, Gilman A. Goodman and Gilman’s Manual of Pharmacology and Therapeutics. Estados Unidos: Mcgraw-Hill; 2014. Available from: https://www.google.com /url?sa=t&source=web&rct=j&opi=89978449&url=http://repo.upertis.ac.id/1824/1/Goodman_Gilman_s_manual_of_Pharmacology_and_Therapeutics.pdf&ved=2ahUKEwjalLzxmeCKAxVtUGwGHaxkHgoQFnoECBQQAQ&usg=AOvVaw2U1LG247fNwFII-AsbAv4Q
Katzung BG. Basic & Clinical Pharmacology (14th ed). New York: Mcgraw-Hill Education; 2018. Available from: https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://pharmacomedicale.org/images/cnpm/CNPM_2016/katzungpharmacology.pdf&ved=2ahUKEwiXrtn6meCKAxXxcGwGHWX0MVoQFnoECBwQAQ&usg=AOvVaw2w2D7rXotwwx9rbShsaVGu
Anekar AA, Cascella M, Hendrix JM. WHO Analgesic Ladder. National Library of Medicine. Treasure Island (FL): StatPearls Publishing; 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554435/
Mufti GR, Tambajong HF, Lalenoh D. Gambaran skala visual analog dan hemodinamik pada pasien yang diberikan kombinasi tramadol dan ketorolak pasca bedah laparotomi. e-CliniC. 2016;4(1):1-7. Doi: http://dx.doi.org/10.35790/ecl.4.1.2016.12133
Ekawati K, Lalenoh D, Kumaat L. Profil nyeri dan perubahan hemodinamik pasca bedah perut bawah dengan ketorolak 30 mg intravena. e-CliniC. 2015;3(1):434-9. Doi: http://dx.doi.org/10.35790/ecl.3.1.2015.7400
Meng ZT, Cui F, Li XY, Wang DX. Epidural morphine improves postoperative analgesia in patients after total knee arthroplasty: a randomized controlled trial. PLOS ONE. 2019;14(7):e0219116. Available from: https://doi.org/10.1371/journal.pone.0219116
Sundarathiti P, Ruananukul N, Channum T, Kitkunasathean C, Mantay A, Thammasakulsiri J, et al. A comparison of continuous femoral nerve block (CFNB) and continuous epidural infusion (CEI) in postoperative analgesia and knee rehabilitation after total knee arthroplasty (TKA). PubMed. 2009;92(3):328–34. Available from: https://www.thaiscience.info/journals/Article/JMAT/10402763.pdf
Prabandari DA, Indriasari I, Maskoen TT. Efektivitas analgesik 24 jam pascaoperasi elektif di RSUP Dr. Hasan Sadikin Bandung tahun 2017. Jurnal Anestesi Perioperatif. 2018;6(2):98–104. Available from: https://journal.fk.unpad.ac.id/index.php/jap/article/view/1221/0
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Julius Julius, Diana C. Lalenoh, Barry I. Kambey

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
COPYRIGHT
Authors who publish with this journal agree to the following terms:
Authors hold their copyright and grant this journal the privilege of first publication, with the work simultaneously licensed under a Creative Commons Attribution License that permits others to impart the work with an acknowledgment of the work's origin and initial publication by this journal.
Authors can enter into separate or additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (for example, post it to an institutional repository or publish it in a book), with an acknowledgment of its underlying publication in this journal.
Authors are permitted and encouraged to post their work online (for example, in institutional repositories or on their website) as it can lead to productive exchanges, as well as earlier and greater citation of the published work (See The Effect of Open Access).


