Characterization of Thelenota ananas and Its Potential as a Natural Source of Antioxidants

Authors

  • Fona D H Budiarso Department of Chemistry, Faculty of Medicine, Sam Ratulangi University
  • Angle Maria Hasthee Sorisi Department of Parasitology, Faculty of Medicine, Sam Ratulangi University
  • Fatimawali Fatimawali Department of Chemistry, Faculty of Medicine, Sam Ratulangi University

DOI:

https://doi.org/10.35799/jbl.v16i1.63976

Keywords:

Thelenota ananas, characterization, antioxidant, DPPH

Abstract

The sea cucumber Thelenota ananas, commonly found in tropical waters, possesses significant biological potential. This study aims to assess the antioxidant potential of Thelenota ananas extract obtained from the Manado sea. The simplicia was analyzed for organoleptic properties, moisture content (9.8%), and ash content (23%). Bioactive compounds were identified through color and foam reactions, while antioxidant activity was measured using the DPPH method. The extract was found to contain saponins, terpenoids, and alkaloids. The antioxidant activity of the extract, with an IC50 value of 99.8 ppm, demonstrates strong antioxidant properties, though less potent than the control, vitamin C (IC50 of 45.5 ppm). These findings suggest that while Thelenota ananas extract exhibits substantial antioxidant activity, it is still less effective than vitamin C. This research highlights the potential of Thelenota ananas as a natural antioxidant source for the development of health products.

References

Afifah Elfath, N., Putri, M. S., Apriandi, A., Teknologi, J., Perikanan, H., Kelautan, I., & Perikanan, D. (2020). MINUMAN FUNGSIONAL TERIPANG PASIR (Holothuria scabra) DAN TERIPANG HITAM (Holothuria atra) Functional Drinks of Sand Sea Cucumber (Holothuria scabra) and Black Sea Cucumber (Holothuria atra). MARINADE, 03(01), 47–58.

Badan POM RI. (2005). Standardisasi Ekstrak Tumbuhan Obat Indonesia, Salah Satu Tahapan Penting Dalam Pengembangan Obat Asli Indonesia. 6, 1–5.

Brand-Williams, W. , C. M. E. , & B. C. (1995). Use of aFree Radical Method to Evaluate Antioxidant Activity. Lebensm. -Wiss. u.-Technology, 28, 25–30.

Dehwie, T., Sumarto, S., & Dahlia, D. (2021). Aktivitas Antioksidan Kulit, Kitin dan Kitosan Teripang Pasir (Holothuria scabra). Jurnal Teknologi Dan Industri Pertanian Indonesia, 13(1), 37–42. https://doi.org/10.17969/jtipi.v13i1.19056

Dolongtelide, J. I., Fatimawali, F., Tallei, T. E., Suoth, E. J., Simbala, H. E. I., Antasionasti, I., & Kalalo, M. J. (2023). In Vitro Antioxidant Activity of Chrysanthemum indicum Flowers Extract and Its Fraction. Malacca Pharmaceutics, 1(2), 43–47. https://doi.org/10.60084/mp.v1i2.26

Farag, R. S., Abdel-Latif, M. S., Abd El Baky, H. H., & Tawfeek, L. S. (2020). Phytochemical screening and antioxidant activity of some medicinal plants’ crude juices. Biotechnology Reports, 28. https://doi.org/10.1016/j.btre.2020.e00536

Ghelani, H., Khursheed, M., Adrian, T. E., & Jan, R. K. (2022). Anti-Inflammatory Effects of Compounds from Echinoderms. In Marine Drugs (Vol. 20, Issue 11). MDPI. https://doi.org/10.3390/md20110693

Harborne J. B. (1998). Phytochemical Methods A Guide to Modern Techniques of Plant Analysis. https://doi.org/10.1007/978-94-009-5921-7

Kumar, Dinesh, Kumar, S., Sahu, M., & Kumar, A. (2020). Evaluation of Pharmacological Features and Nanoparticle Formation by Urena lobata. Haya: The Saudi Journal of Life Sciences, 5(10), 226–235. https://doi.org/10.36348/sjls.2020.v05i10.006

Leyane, T. S., Jere, S. W., & Houreld, N. N. (2022). Oxidative Stress in Ageing and Chronic Degenerative Pathologies: Molecular Mechanisms Involved in Counteracting Oxidative Stress and Chronic Inflammation. In International Journal of Molecular Sciences (Vol. 23, Issue 13). MDPI. https://doi.org/10.3390/ijms23137273

Liguori, I., Russo, G., Curcio, F., Bulli, G., Aran, L., Della-Morte, D., Gargiulo, G., Testa, G., Cacciatore, F., Bonaduce, D., & Abete, P. (2018). Oxidative stress, aging, and diseases. In Clinical Interventions in Aging (Vol. 13, pp. 757–772). Dove Medical Press Ltd. https://doi.org/10.2147/CIA.S158513

Nwozo, O. S., Effiong, E. M., Aja, P. M., & Awuchi, C. G. (2023). Antioxidant, phytochemical, and therapeutic properties of medicinal plants: a review. In International Journal of Food Properties (Vol. 26, Issue 1, pp. 359–388). Taylor and Francis Ltd. https://doi.org/10.1080/10942912.2022.2157425

Pangestuti, R., & Arifin, Z. (2018b). Medicinal and health benefit effects of functional sea cucumbers. In Journal of Traditional and Complementary Medicine (Vol. 8, Issue 3, pp. 341–351). National Taiwan University. https://doi.org/10.1016/j.jtcme.2017.06.007

Prasetyo, E., Zukhruf, N., Kharomah, W., Pudji, T., Program, R., Farmasi, S., Sarjana, P., Gombong, S. M., & Kebumen, J. (2021). Uji Aktivitas Antioksidan Menggunakan Metode DPPH (2,2-difenil-1-pikrilhidrazil) Terhadap Ekstrak Etanol Kulit Buah Durian (Durio zibethinnus L.) dari Desa Alasmalang Kabupaten Banyumas. In Jurnal Pharmascience (Vol. 08, Issue 01). https://ppjp.ulm.ac.id/journal/index.php/pharmascience

Sukmiwati, M., Karnila, R., & Putri, D. A. (2024). Antioxidant Potency of Transparent Sea Cucumber (Paracaudina australis). Jurnal Pengolahan Hasil Perikanan Indonesia, 27(2), 124–131. https://doi.org/10.17844/jphpi.v27i2.46969

Downloads

Published

2026-03-31

How to Cite

Budiarso, F., Sorisi, A., & Fatimawali, F. (2026). Characterization of Thelenota ananas and Its Potential as a Natural Source of Antioxidants. JURNAL BIOS LOGOS, 16(1), 25–33. https://doi.org/10.35799/jbl.v16i1.63976

Issue

Vol. 16 No. 1 (2026): JURNAL BIOS LOGOS

Section

Articles

License

Copyright (c) 2026 Fona D H Budiarso, Angle Maria Hasthee Sorisi, Fatimawali Fatimawali

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Most read articles by the same author(s)